2. Gene
  3. Ltb - lymphotoxin B Gene

Ltb - lymphotoxin B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: p33; Tnfc; LTbeta; Tnfsf3; Tnlg1c

基因 ID: 16994 | 基因类型: protein coding

关于 Ltb

功能概要

Predicted to enable cytokine activity and tumor necrosis factor receptor binding activity. Involved in positive regulation of interleukin-12 production. Acts upstream of or within gene expression; lymph node development; and skin development. Predicted to be located in plasma membrane. Is expressed in several structures, including brain; hemolymphoid system; liver; lung; and reproductive system. Orthologous to human LTB (lymphotoxin beta). [provided by Alliance of Genome Resources, Apr 2022]

Ltb 基因产物(1)

mRNA Protein Name
NM_008518.2 NP_032544.1 lymphotoxin-beta
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within gene expression IMP
IMP: 通过突变表型推断
17673451 MGI
acts upstream of or within lymph node development IMP
IMP: 通过突变表型推断
9133428 MGI
involved in positive regulation of interleukin-12 production IMP
IMP: 通过突变表型推断
17982081 MGI
acts upstream of or within skin development IMP
IMP: 通过突变表型推断
17673451 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lymphotoxin-beta

LT-beta

TNF-C

tumor necrosis factor C

tumor necrosis factor ligand 1c

tumor necrosis factor ligand superfamily member 3

相关产品

Approval
生物活性分子 (3)
目录号 产品名 作用方式
纯度 是否罕见病
HY-I0021 Bepotastine Antagonist 98.58% 否
HY-A0015 Bepotastine besilate Antagonist 99.77% 否
HY-I0021A Bepotastine tosylate Antagonist / 否
Clinical Phase
生物活性分子 (8)
目录号 产品名 作用方式
纯度 Phase
HY-107608 Leukotriene B4 ≥98.0% Phase 2
HY-15874 Fiboflapon Inhibitor 99.50% Phase 2
HY-13628 Etalocib 99.03% Phase 2
HY-112737 LY223982 Inhibitor 99.65% Phase 2
HY-19304 Amelubant Antagonist 98.45% Phase 2
HY-15874A Fiboflapon sodium Inhibitor 99.46% Phase 2
HY-105176 Ontazolast Inhibitor / Phase 2
HY-19193 CP-105696 Antagonist 99.93% Phase 1
Pre-clinical Phase
生物活性分子 (87)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-103360 J-113863 Antagonist ≥99.0% 否
HY-101408 Docosatrienoic Acid 98.68% 否
HY-114641A BIIL-260 hydrochloride Antagonist 99.90% 否
HY-15744 LY255283 Antagonist 98.04% 否
HY-W073687 2,4,6-Triiodophenol Inducer 99.52% 否
HY-108396 γ-Linolenic acid ethyl ester Antagonist 99.14% 否
HY-N1942 5-O-Demethylnobiletin Inhibitor 99.91% 否
HY-106929 Moxilubant Antagonist 99.83% 否
HY-156736 HSD17B13-IN-3 Inhibitor 99.78% 否
HY-113483 20-Carboxy-Leukotriene B4 Inhibitor 98.0% 否
HY-149589 11(Z),14(Z)-Eicosadienoic acid Inhibitor ≥98.0% 否
HY-101438 Darbufelone Inhibitor 99.49% 否
HY-107608S Leukotriene B4-d4 99.1% 否
HY-A0015A (Rac)-Bepotastine besilate Inhibitor 99.52% 否
HY-101438A Darbufelone mesylate Inhibitor 99.65% 否
HY-112741 SB-209247 Antagonist 99.33% 否
HY-161212 HSD17B13-IN-8 Inhibitor 99.97% 否
HY-19443 UCB-35440 / 否
HY-12995A (S)-BI 665915 Inhibitor / 否
HY-10437 Setileuton Inhibitor / 否
HY-10437A Setileuton tosylate Inhibitor / 否
HY-106929B Moxilubant hydrochloride Antagonist / 否
HY-107608A 5(S),12(S)-Leukotriene B4 / 否
HY-112621 Leukotriene A4 methyl ester / 否
HY-112742 CP-195543 Antagonist / 否
HY-113479 20-Hydroxy-leukotriene B4 / 否
HY-113484 Leukotriene B5 Activator / 否
HY-113879 18-Carboxy dinor Leukotriene B4 / 否
HY-114641 BIIL-260 Antagonist / 否
HY-115369 Methyl (13Z,16Z,19Z)-docosatrienoate / 否
HY-115390 14,15-Dehydro Leukotriene B4 Antagonist / 否
HY-117896 SC-50605 Antagonist / 否
HY-120539 Enofelast Inhibitor / 否
HY-121621 RO5101576 / 否
HY-123008 Reproterol hydrochloride / 否
HY-123014 (Rac)-SC-45694 Agonist / 否
HY-123575 LY 245769 Inhibitor / 否
HY-124100 LTB4 antagonist 4 / 否
HY-12995 BI 665915 Inhibitor / 否
HY-130497 12-Oxo-leukotriene B4 / 否
HY-131651 Leukotriene B4 ethanolamide Antagonist / 否
HY-134123 Lipoxin B4 methyl ester / 否
HY-13628A Etalocib sodium / 否
HY-137350 12-epi-LTB4 Agonist / 否
HY-138050 Nyasol Inhibitor / 否
HY-139112 Leukotriene B4 dimethyl amide / 否
HY-14165A (S)-Veliflapon Inhibitor 99.44% 否
HY-149082 LTB4 antagonist 1 Antagonist / 否
HY-149083 LTB4 antagonist 2 Antagonist / 否
HY-149084 LTB4 antagonist 3 Antagonist / 否
HY-155204 LTB4-IN-2 Inhibitor / 否
HY-155300 BLT2 antagonist-1 Antagonist / 否
HY-168015 5-Oxo leukotriene B4 / 否
HY-169434 LTB Inhibitor / 否
HY-169435 TK-OH 98.36% 否
HY-169436 Lon-TK Inhibitor / 否
HY-19114 WY-50295 Inhibitor / 否
HY-CE00537 18-CoA-18-oxo-dinor-LTB4 / 否
HY-N7801 (±)5-HEPE / 否
HY-RS07872 LTB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07873 LTB4R Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07874 Ltb4r Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07875 Ltb4r1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07876 LTB4R2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W341962 Halometasone Inhibitor 98.47% 否
HY-W744842 γ-Linolenic acid ethyl ester-d5 / 否
HY-W747565 Leukotriene B4-3-aminopropylamide / 否
HY-101579 LY 178002 / 否
HY-107608S1 Leukotriene B4-d5 / 否
HY-113628 ABT-080 Inhibitor / 否
HY-117557 LY306669 Antagonist / 否
HY-117706 LY 292728 Antagonist / 否
HY-117854 SB 201146 Antagonist / 否
HY-118156 L-699333 / 否
HY-118848 A63162 Inhibitor / 否
HY-120606 A-78773 Inhibitor / 否
HY-122536 Ricinelaidic acid / 否
HY-14162 AM103 free acid Inhibitor / 否
HY-141635 cis-11,14-Eicosadienoic acid methyl ester / 否
HY-174587 Human LTB mRNA / 否
HY-RS16892 Ltb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23334 Ltb Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-100173 DW-1350 Antagonist / 否
HY-112650 12-OxoETE / 否
HY-U00170 Bunaprolast Inhibitor / 否
HY-U00263 LY210073 Antagonist / 否
HY-U00299 LTB4-IN-1 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ltb NCBI NCBI:4050
Macaca fascicularis Ltb NCBI NCBI:102135554
Rattus norvegicus Ltb NCBI NCBI:361795
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