2. Gene
  3. Mcm2 - minichromosome maintenance complex component 2 Gene

Mcm2 - minichromosome maintenance complex component 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: BM28; CDCL1; Mcmd2; mKIAA0030

基因 ID: 17216 | 基因类型: protein coding

关于 Mcm2

功能概要

Enables DNA replication origin binding activity; enzyme binding activity; and histone binding activity. Acts upstream of or within DNA unwinding involved in DNA replication; cellular response to interleukin-4; and nucleosome assembly. Located in nucleus. Part of nuclear origin of replication recognition complex. Is expressed in several structures, including central nervous system; future brain; inner cell mass; limb; and vertebral axis musculature. Human ortholog(s) of this gene implicated in Alzheimer's disease and autosomal dominant nonsyndromic deafness 70. Orthologous to human MCM2 (minichromosome maintenance complex component 2). [provided by Alliance of Genome Resources, Apr 2022]

Mcm2 基因产物(1)

mRNA Protein Name
NM_008564.2 NP_032590.2 DNA replication licensing factor MCM2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA replication origin binding IDA
IDA: 通过直接分析推断
12941272 MGI
enables enzyme binding IPI
IPI: 通过物理相互作用推断
24115439 MGI
enables histone binding IDA
IDA: 通过直接分析推断
10531422 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within DNA unwinding involved in DNA replication IDA
IDA: 通过直接分析推断
10531422 MGI
acts upstream of or within cellular response to interleukin-4 IDA
IDA: 通过直接分析推断
9798653 MGI
acts upstream of or within nucleosome assembly IDA
IDA: 通过直接分析推断
10531422 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of MCM complex IDA
IDA: 通过直接分析推断
10567526 MGI
part of nuclear origin of replication recognition complex IDA
IDA: 通过直接分析推断
12941272 MGI
located in nucleus IDA
IDA: 通过直接分析推断
10531422 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

DNA replication licensing factor MCM2

mini chromosome maintenance deficient 2

minichromosome maintenance deficient 2 mitotin

minichromosome maintenance protein 2 homolog

nuclear protein BM28

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-143432A (S)-Cdc7-IN-18 Inhibitor / 否
HY-RS08234 MCM2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08240 MCM7 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17409 Mcm2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23863 Mcm2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mcm2 NCBI NCBI:4171
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