2. Gene
  3. Msc - musculin Gene

Msc - musculin Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: MyoR; bHLHa22

基因 ID: 17681 | 基因类型: protein coding

关于 Msc

功能概要

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; roof of mouth development; and skeletal muscle organ development. Acts upstream of or within cellular response to Leukemia Inhibitory Factor. Located in nucleus. Is expressed in several structures, including branchial arch; foregut; limb bud; musculature; and trunk mesenchyme. Orthologous to human MSC (musculin). [provided by Alliance of Genome Resources, Apr 2022]

Msc 基因产物(5)

mRNA Protein Name
NM_001360810.2 NP_001347739.1 musculin isoform 2
NM_001411711.1 NP_001398640.1 musculin isoform 3
NM_001411712.1 NP_001398641.1 musculin isoform 4
NM_001411713.1 NP_001398642.1 musculin isoform 5
NM_010827.3 NP_034957.1 musculin isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
9892671 MGI
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IMP
IMP: 通过突变表型推断
9892671 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
9892671 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in branchiomeric skeletal muscle development IGI
IGI: 通过遗传相互作用推断
12493912 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
involved in diaphragm development IGI
IGI: 通过遗传相互作用推断
12493912 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
9892671 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
9892671 MGI
involved in roof of mouth development IGI
IGI: 通过遗传相互作用推断
12493912 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
19796622 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

musculin

myogenic repressor

相关产品

Clinical Phase
生物活性分子 (4)
目录号 产品名 作用方式
纯度 Phase
HY-101215 Evobrutinib Inhibitor 98.70% Phase 3
HY-12042 Pimasertib Inhibitor 99.60% Phase 2
HY-135827A Roginolisib hemifumarate Inhibitor 99.80% Phase 2
HY-100501 M2698 Inhibitor 99.87% Phase 1
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P990461 Anti-LIF Antibody (MSC-1) Inhibitor 98.51% Phase 1
Pre-clinical Phase
生物活性分子 (36)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P1410 GsMTx4 Inhibitor 99.83% 否
HY-P1410A GsMTx4 TFA Inhibitor 99.80% 否
HY-P1410C D-GsMTx4 TFA Inhibitor 99.89% 否
HY-123872 MSC1094308 Inhibitor 99.89% 否
HY-P1410B D-GsMTx4 Inhibitor 99.59% 否
HY-132301 MSC-4381 Inhibitor 98.89% 否
HY-101611 MSC2530818 Inhibitor 99.62% 否
HY-147208 MSC-4106 Inhibitor 99.87% 否
HY-148518 MSC-1186 Inhibitor 98.95% 否
HY-N0898A (-)-Catechin Inhibitor 98.78% 否
HY-108628 SU16f Inhibitor 99.36% 否
HY-135827 Roginolisib Inhibitor 99.66% 否
HY-110218 CW 008 Agonist 98.15% 否
HY-N0008 Orcinol glucoside 99.57% 否
HY-B1890 (±)-Catechin Inhibitor 98.80% 否
HY-123851 MSC2504877 Inhibitor 98.50% 否
HY-126225 SJA710-6 99.62% 否
HY-131032 KI-7 Agonist 99.16% 否
HY-108438 TCS 2210 Inducer / 否
HY-110262 MSC 2032964A Inhibitor / 否
HY-113568 CAY10581 Inhibitor / 否
HY-12042A Pimasertib hydrochloride Inhibitor / 否
HY-147511 PPARγ agonist 7 Agonist / 否
HY-160053 Gint4.T aptamer sodium Chemical / 否
HY-168506 MSC-1254 Inhibitor / 否
HY-170581 PPARγ/δ modulator 2 Modulator / 否
HY-170837 STAT5-IN-3 Inhibitor / 否
HY-N0008R Orcinol glucoside (Standard) / 否
HY-N8917 (3R)-7-hydroxy-3-(4-hydroxybenzyl)chromane Activator / 否
HY-RS08707 MSC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS13119 SLC25A37 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-153332 Tankyrase-IN-5 Inhibitor / 否
HY-168505 MSC-5046 Inhibitor / 否
HY-177058 DSP30 Agonist / 否
HY-RS17017 Msc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23460 Msc Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Msc NCBI NCBI:9242
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