1. Cell Cycle/DNA Damage
  2. p97
  3. MSC1094308

MSC1094308 

目录号: HY-123872
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MSC1094308 是一种可逆的、II 型 AAA ATPase (VCP)/p97 和I型 AAA ATPase VPS4B 的变构抑制剂,对VPS4B 和 p97 的IC50 值分别为 0.71 μM 和 7.2 μM。

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MSC1094308 Chemical Structure

MSC1094308 Chemical Structure

CAS No. : 2219320-08-6

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Description

MSC1094308 is a reversible and allosteric inhibitor of the type II AAA ATPase human ubiquitin-directed unfoldase (VCP)/p97 and the type I AAA ATPase VPS4B, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively[1].

IC50 & Target

IC50: 0.71 μM (VPS4B), 7.2 μM (p97)[1].

Molecular Weight

462.55

Formula

C₂₉H₂₉F₃N₂

CAS No.

2219320-08-6

SMILES

FC1=CC=C(C(C2=CC=C(F)C=C2)CCCNCC3CCC(NC4=C5C=C(F)C=C4)=C5C3)C=C1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
MSC1094308
目录号:
HY-123872
需求量:

MSC1094308

Cat. No.: HY-123872