2. Metabolic Enzyme/Protease
  3. Indoleamine 2,3-Dioxygenase (IDO)
  4. CAY10581

CAY10581 是一种吡喃萘醌衍生物，是一种高度特异性和可逆的非竞争性 IDO 抑制剂，IC50 为 55 nM。

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CAY10581 Chemical Structure

CAY10581 Chemical Structure

CAS No. : 1018340-07-2

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规格 价格 是否有货 数量
1 mg ￥778
3 - 4 周
5 mg   询价  
10 mg   询价  

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Customer Review

CAY10581 相关抗体

Top Publications Citing Use of Products

查看 Indoleamine 2,3-Dioxygenase (IDO) 亚型特异性产品:

查看所有亚型
IDO1 IDO2 IDO

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

CAY10581, a pyranonaphthoquinone derivative, is a highly specific and reversible uncompetitive IDO Inhibitor with an IC50 of 55 nM[1][2].

IC50 & Target[2]

IDO

55 nM (IC50)

体外研究
(In Vitro)

CAY10581 (100 nM; 24 小时) 消除 IFN-γ 在 MSCs 中的生长抑制[1]。
CAY10581 (化合物 36) 在 100 μM 浓度下 24 小时后对 T-REx 细胞活力的影响极小[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAY10581 相关抗体:

Cell Viability Assay[1]

Cell Line: Mesenchymal stem cells (MSCs)
Concentration: 100 nM
Incubation Time: 24 h post-treatment
Result: Abrogated the growth inhibition by IFN-gamma (50 ng/ml) in MSCs.
分子量

363.41

Formula

C22H21NO4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

CAY10581 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CAY105811018340-07-2CAY 10581CAY-10581Indoleamine 2,3-Dioxygenase (IDO)PyranonaphthoquinonereversibleuncompetitiveMSCsInhibitorinhibitorinhibit

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产品名称：
CAY10581
目录号：
HY-113568
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