2. Gene
  3. Ptgs1 - prostaglandin-endoperoxide synthase 1 Gene

Ptgs1 - prostaglandin-endoperoxide synthase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: COX1; Cox-1; Cox-3; PHS 1; Pghs1; PGHS-1

基因 ID: 19224 | 基因类型: protein coding

关于 Ptgs1

功能概要

This is one of two genes encoding similar Enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. [provided by RefSeq, Jan 2014]

Ptgs1 基因产物(1)

mRNA Protein Name
NM_008969.4 NP_032995.1 prostaglandin G/H synthase 1 precursor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within prostaglandin biosynthetic process IMP
IMP: 通过突变表型推断
12093889 MGI
acts upstream of or within prostaglandin metabolic process IMP
IMP: 通过突变表型推断
10987272 MGI
acts upstream of or within regulation of blood pressure IMP
IMP: 通过突变表型推断
12093889 MGI
acts upstream of or within regulation of cell population proliferation IGI
IGI: 通过遗传相互作用推断
10987272 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12021206 MGI
NOT located in nucleus IDA
IDA: 通过直接分析推断
12021206 MGI
located in photoreceptor outer segment IDA
IDA: 通过直接分析推断
12355421 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

prostaglandin G/H synthase 1

PGH synthase 1

cyclooxygenase-1

prostaglandin H2 synthase 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11392 PTGS1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19231 Ptgs1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25720 Ptgs1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptgs1 NCBI NCBI:5742
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