2. Gene
  3. Tle1 - transducin-like enhancer of split 1 Gene

Tle1 - transducin-like enhancer of split 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Grg1; Grg-1; Tle4l; Estm14; C230057C06Rik

基因 ID: 21885 | 基因类型: protein coding

关于 Tle1

功能概要

Enables chromatin binding activity and transcription corepressor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human TLE1 (TLE family member 1, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Tle1 基因产物(5)

mRNA Protein Name
NM_001285529.1 NP_001272458.1 transducin-like enhancer protein 1 isoform b
NM_001285530.1 NP_001272459.1 transducin-like enhancer protein 1 isoform c
NM_001285531.1 NP_001272460.1 transducin-like enhancer protein 1 isoform d
NM_001285532.1 NP_001272461.1 transducin-like enhancer protein 1 isoform e
NM_011599.5 NP_035729.3 transducin-like enhancer protein 1 isoform a
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
16002402 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12359720 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
15528197 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
12359720 MGI
acts upstream of or within regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
15528197 MGI
acts upstream of or within regulation of transcription by RNA polymerase II IGI
IGI: 通过遗传相互作用推断
15528197 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
12359720 MGI
part of transcription regulator complex IDA
IDA: 通过直接分析推断
15528197 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transducin-like enhancer protein 1

groucho-related protein 1

transducin-like enhancer of split 1, homolog of Drosophila E(spl)

transducin-like enhancer of split 4 (homolog of Drosophila E(spl)) - like

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14563 TLE1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-P10488 cycFWRPW Activator / 否
HY-RS21443 Tle1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27961 Tle1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tle1 NCBI NCBI:7088
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