2. Gene
  3. Ywhaz - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide Gene

Ywhaz - tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: 14-3-3zeta; 1110013I11Rik

基因 ID: 22631 | 基因类型: protein coding

关于 Ywhaz

功能概要

Enables protein domain specific binding activity. Involved in several processes, including respiratory system process; synaptic target recognition; and tube morphogenesis. Acts upstream of or within ERK1 and ERK2 cascade; protein targeting; and regulation of cell death. Located in hippocampal mossy fiber to CA3 synapse and nucleus. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Used to study schizophrenia. Orthologous to human YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). [provided by Alliance of Genome Resources, Apr 2022]

Ywhaz 基因产物(5)

mRNA Protein Name
NM_001253805.1 NP_001240734.1 14-3-3 protein zeta/delta isoform 1
NM_001253806.1 NP_001240735.1 14-3-3 protein zeta/delta isoform 1
NM_001253807.1 NP_001240736.1 14-3-3 protein zeta/delta isoform 2
NM_001356569.1 NP_001343498.1 14-3-3 protein zeta/delta isoform 1
NM_011740.3 NP_035870.1 14-3-3 protein zeta/delta isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
11124266 MGI
enables protein domain specific binding IDA
IDA: 通过直接分析推断
12176995 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within ERK1 and ERK2 cascade IMP
IMP: 通过突变表型推断
29118970 MGI
acts upstream of or within angiogenesis IGI
IGI: 通过遗传相互作用推断
29118970 MGI
involved in angiogenesis IMP
IMP: 通过突变表型推断
29118970 MGI
involved in lung development IMP
IMP: 通过突变表型推断
29118970 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
21621563 MGI
acts upstream of or within protein targeting IDA
IDA: 通过直接分析推断
12446771 MGI
acts upstream of or within regulation of programmed cell death IGI
IGI: 通过遗传相互作用推断
19451227 MGI
involved in respiratory system process IMP
IMP: 通过突变表型推断
29118970 MGI
involved in synaptic target recognition IDA
IDA: 通过直接分析推断
22124272 MGI
involved in synaptic target recognition IMP
IMP: 通过突变表型推断
22124272 MGI
acts upstream of or within tube formation IGI
IGI: 通过遗传相互作用推断
29118970 MGI
involved in tube formation IMP
IMP: 通过突变表型推断
29118970 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: 通过直接分析推断
22124272 MGI
is active in hippocampal mossy fiber to CA3 synapse IMP
IMP: 通过突变表型推断
22124272 MGI
located in nucleus IDA
IDA: 通过直接分析推断
15615787 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

14-3-3 protein zeta/delta

14-3-3 zeta

KCIP-1

SEZ-2

protein kinase C inhibitor protein 1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15945 YWHAZ Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18690 Ywhaz Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25176 Ywhaz Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ywhaz NCBI NCBI:7534
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