1. Gene
  2. Aimp2 - aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 Gene

Aimp2 - aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 Gene

种属: Mus musculus

同用名: Jtv1; Aimp2(p38)

基因 ID: 231872 | 基因类型: protein coding

关于 Aimp2

功能概要

Enables molecular adaptor activity. Involved in positive regulation of aminoacyl-tRNA Ligase activity and protein-containing complex assembly. Acts upstream of or within negative regulation of cell population proliferation; positive regulation of protein ubiquitination; and type II pneumocyte differentiation. Located in nucleus. Part of Aminoacyl-tRNA Synthetase multienzyme complex. Is expressed in several structures, including olfactory epithelium; orbito-sphenoid; submandibular gland primordium; thymus primordium; and tooth. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human AIMP2 (aminoacyl tRNA synthetase complex interacting multifunctional protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Aimp2 基因产物(2)

mRNA Protein Name
NM_001172146.1 NP_001165617.1 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform 1
NM_146165.2 NP_666277.1 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables molecular adaptor activity IMP
IMP: 通过突变表型推断
12060739 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12060739 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within negative regulation of cell population proliferation IDA
IDA: 通过直接分析推断
12819782 MGI
acts upstream of or within positive regulation of protein ubiquitination IDA
IDA: 通过直接分析推断
12819782 MGI
acts upstream of protein ubiquitination IDA
IDA: 通过直接分析推断
12819782 MGI
involved in protein-containing complex assembly IMP
IMP: 通过突变表型推断
12060739 MGI
acts upstream of or within type II pneumocyte differentiation IMP
IMP: 通过突变表型推断
12819782 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of aminoacyl-tRNA synthetase multienzyme complex IMP
IMP: 通过突变表型推断
12060739 MGI
located in nucleus IDA
IDA: 通过直接分析推断
12819782 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

aminoacyl tRNA synthase complex-interacting multifunctional protein 2

ARS interacting multifunctional protein 2

multisynthase complex auxiliary component p38

multisynthetase complex auxiliary component p38

protein JTV-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aimp2 NCBI NCBI:7965