Scn11a - sodium channel, voltage-gated, type XI, alpha Gene

中文名称：钠通道，电压门控，X I 型， α

种属: Mus musculus

同用名: NaN; NaT; NSS2; SNS2; NaV1.9

关于 Scn11a

功能概要

该基因编码的蛋白可启动电压门控钠通道活动。参与调节疼痛的感官知觉。作用于钠离子运输的上游或内部。位于C-纤维和质膜。以多种结构表达，包括消化系统；中枢神经系统;免疫系统;肝脏和胆道系统；和生殖系统。用于研究家族性发作性疼痛综合征 3 和遗传性感觉神经病。该基因的人类直向同源物与家族性发作性疼痛综合征 3 和遗传性感觉和自主神经病 7 型有关。与人类 SCN11A（钠电压门控通道 α 亚基 11）直向同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables voltage-gated Sodium Channel activity. Involved in regulation of sensory perception of pain. Acts upstream of or within sodium ion transport. Located in C-fiber and plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; immune system; liver and biliary system; and reproductive system. Used to study familial episodic pain syndrome 3 and hereditary sensory neuropathy. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 3 and hereditary sensory and autonomic neuropathy type 7. Orthologous to human SCN11A (sodium voltage-gated channel alpha subunit 11). [provided by Alliance of Genome Resources, Apr 2022]