2. Gene
  3. Gfap - glial fibrillary acidic protein Gene

Gfap - glial fibrillary acidic protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 24387 | 基因类型: protein coding

关于 Gfap

功能概要

Enables Integrin binding activity and kinase binding activity. A structural constituent of Cytoskeleton. Involved in positive regulation of glial cell proliferation; regulation of chaperone-mediated autophagy; and response to wounding. Located in astrocyte projection and cytoplasmic side of lysosomal membrane. Biomarker of brain edema and retinal disease. Human ortholog(s) of this gene implicated in Alexander disease. Orthologous to human GFAP (glial fibrillary acidic protein). [provided by Alliance of Genome Resources, Apr 2022]

Gfap 基因产物(1)

mRNA Protein Name
NM_017009.2 NP_058705.2 glial fibrillary acidic protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables integrin binding IDA
IDA: 通过直接分析推断
16988027 RGD
enables kinase binding IPI
IPI: 通过物理相互作用推断
11082283 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
20797626 RGD
enables structural constituent of cytoskeleton IDA
IDA: 通过直接分析推断
11796520 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of glial cell proliferation IMP
IMP: 通过突变表型推断
21250919 RGD
involved in regulation of chaperone-mediated autophagy IMP
IMP: 通过突变表型推断
20797626 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in astrocyte projection IDA
IDA: 通过直接分析推断
12368262 RGD
located in cytoplasmic side of lysosomal membrane IDA
IDA: 通过直接分析推断
20797626 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glial fibrillary acidic protein

glial fibrillary acidic protein alpha

glial fibrillary acidic protein delta

intermediate filament

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P3392 Zilganersen 91.43% Phase 3
Pre-clinical Phase
生物活性分子 (7)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148013 K284-6111 Inhibitor 99.94% 否
HY-W019710 (E,E)-RGFP966 Inhibitor 99.31% 否
HY-P3392A Zilganersen sodium Inhibitor 91.43% 否
HY-176311S GFAP, U-15N / 否
HY-RS05376 GFAP Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17035 Gfap Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23479 Gfap Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gfap NCBI NCBI:2670
Mus musculus Gfap NCBI NCBI:14580
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