2. Gene
  3. Htr1b - 5-hydroxytryptamine receptor 1B Gene

Htr1b - 5-hydroxytryptamine receptor 1B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25075 | 基因类型: protein coding

关于 Htr1b

功能概要

Enables G protein-coupled serotonin receptor activity; heterocyclic compound binding activity; and voltage-gated Calcium Channel activity involved in regulation of presynaptic cytosolic calcium levels. Involved in several processes, including modulation of chemical synaptic transmission; regulation of amine transport; and response to cocaine. Located in plasma membrane. Is active in calyx of Held. Used to study anxiety disorder. Biomarker of hypertension; ischemia; and obesity. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder and conduct disorder. Orthologous to human HTR1B (5-hydroxytryptamine receptor 1B). [provided by Alliance of Genome Resources, Apr 2022]

Htr1b 基因产物(1)

mRNA Protein Name
NM_022225.2 NP_071561.1 5-hydroxytryptamine receptor 1B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled serotonin receptor activity IDA
IDA: 通过直接分析推断
15328035 RGD
enables heterocyclic compound binding IDA
IDA: 通过直接分析推断
16546225 RGD
enables voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels EXP
EXP: 通过实验结果推断
17067296 RGD
enables voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels IDA
IDA: 通过直接分析推断
17067296 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in chemical synaptic transmission IDA
IDA: 通过直接分析推断
15328035 RGD
involved in drinking behavior IMP
IMP: 通过突变表型推断
16839853 RGD
involved in feeding behavior IMP
IMP: 通过突变表型推断
12373419 RGD
involved in negative regulation of gamma-aminobutyric acid secretion IDA
IDA: 通过直接分析推断
30217553 RGD
involved in negative regulation of synaptic transmission, GABAergic IMP
IMP: 通过突变表型推断
17229091 RGD
involved in negative regulation of synaptic transmission, glutamatergic IMP
IMP: 通过突变表型推断
17392733 RGD
involved in presynaptic modulation of chemical synaptic transmission EXP
EXP: 通过实验结果推断
17067296 RGD
involved in presynaptic modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
17067296 RGD
involved in regulation of dopamine secretion IMP
IMP: 通过突变表型推断
16885935 RGD
involved in regulation of synaptic vesicle exocytosis EXP
EXP: 通过实验结果推断
17067296 RGD
involved in regulation of synaptic vesicle exocytosis IDA
IDA: 通过直接分析推断
17067296 RGD
involved in response to cocaine IDA
IDA: 通过直接分析推断
17509084 RGD
involved in response to ethanol IMP
IMP: 通过突变表型推断
16212943 RGD
involved in response to mineralocorticoid IEP
IEP: 通过表达模式推断
11882579 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in calyx of Held EXP
EXP: 通过实验结果推断
17067296 RGD
is active in calyx of Held IDA
IDA: 通过直接分析推断
17067296 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

5-hydroxytryptamine receptor 1B

5-HT-1B

5-HT1B serotonin receptor

5-hydroxytryptamine (serotonin ) receptor 1B

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

serotonin (5-hydroxytryptamine (5HT)) receptor type 1B

serotonin receptor 1B

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06461 HTR1B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20424 Htr1b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26933 Htr1b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Htr1b NCBI NCBI:3351
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