2. Gene
  3. Acsl1 - acyl-CoA synthetase long-chain family member 1 Gene

Acsl1 - acyl-CoA synthetase long-chain family member 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: ACS; Acas; COAA; Facl2

基因 ID: 25288 | 基因类型: protein coding

关于 Acsl1

功能概要

Enables arachidonate-CoA Ligase activity; oleoyl-CoA Ligase activity; and phytanate-CoA Ligase activity. Involved in several processes, including fatty acid metabolic process; long-chain fatty-acyl-CoA biosynthetic process; and positive regulation of long-chain fatty acid import across plasma membrane. Located in bounding membrane of organelle; endoplasmic reticulum; and plasma membrane. Biomarker of obesity. Orthologous to human ACSL1 (acyl-CoA synthetase long chain family member 1). [provided by Alliance of Genome Resources, Apr 2022]

Acsl1 基因产物(1)

mRNA Protein Name
NM_012820.2 NP_036952.1 long-chain-fatty-acid--CoA ligase 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables arachidonate-CoA ligase activity IDA
IDA: 通过直接分析推断
28209804 RGD
enables long-chain fatty acid-CoA ligase activity IDA
IDA: 通过直接分析推断
10198260 RGD
enables oleoyl-CoA ligase activity IMP
IMP: 通过突变表型推断
23024797 RGD
enables phytanate-CoA ligase activity IDA
IDA: 通过直接分析推断
8978480 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in fatty acid metabolic process IMP
IMP: 通过突变表型推断
17028193 RGD
involved in fatty acid transport IGI
IGI: 通过遗传相互作用推断
16466685 RGD
involved in long-chain fatty acid import into cell IMP
IMP: 通过突变表型推断
23024797 RGD
involved in long-chain fatty acid metabolic process IDA
IDA: 通过直接分析推断
10749848 RGD
involved in long-chain fatty-acyl-CoA biosynthetic process IGI
IGI: 通过遗传相互作用推断
16466685 RGD
involved in positive regulation of long-chain fatty acid import across plasma membrane IDA
IDA: 通过直接分析推断
24503477 RGD
involved in response to nutrient IEP
IEP: 通过表达模式推断
15811777 RGD
involved in response to oleic acid IEP
IEP: 通过表达模式推断
16428347 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
10777552 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
16428347 RGD
involved in triglyceride biosynthetic process IGI
IGI: 通过遗传相互作用推断
16466685 RGD
involved in very long-chain fatty acid metabolic process IDA
IDA: 通过直接分析推断
8978480 RGD
involved in xenobiotic catabolic process IDA
IDA: 通过直接分析推断
10725307 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
17478130 RGD
located in mitochondrion IDA
IDA: 通过直接分析推断
24503477 RGD
located in mitochondrion IMP
IMP: 通过突变表型推断
23024797 RGD
located in peroxisomal membrane IDA
IDA: 通过直接分析推断
14561759 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

long-chain-fatty-acid--CoA ligase 1

Acyl CoA synthetase, long chain

LACS 1

arachidonate--CoA ligase

fatty acid Coenzyme A ligase, long chain 2

long-chain acyl-CoA synthetase 1

long-chain-fatty-acid--CoA ligase, liver isozyme

phytanate--CoA ligase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00200 ACSL1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16255 Acsl1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24003 Acsl1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acsl1 NCBI NCBI:2180
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