CABYR - calcium binding tyrosine phosphorylation regulated Gene

中文名称：钙结合酪氨酸磷酸化调节

种属: Homo sapiens

同用名: CT88; FSP2; CBP86; FSP-2; CABYRa; CABYRc; CABYRe; CABYRc/d

关于 CABYR

功能概要

为了达到受精能力，精子经历了一系列形态学和分子成熟过程，称为获能，涉及蛋白质酪氨酸磷酸化和细胞内钙增加。由该基因编码的蛋白质定位于与纤维鞘相关的精子鞭毛的主要部分，并在获能过程中磷酸化时表现出钙结合。已为该基因鉴定了 3 号染色体上的假基因。已发现该基因编码不同蛋白质亚型的可变剪接转录物变体。[RefSeq 提供，2013 年 7 月]

To reach fertilization competence, spermatozoa undergo a series of morphological and molecular maturational processes, termed capacitation, involving protein tyrosine phosphorylation and increased intracellular calcium. The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation. A pseudogene on chromosome 3 has been identified for this gene. Alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq, Jul 2013]