Cc2d1a - coiled-coil and C2 domain containing 1A Gene

种属: Rattus norvegicus

同用名: RGD1306108

关于 Cc2d1a

功能概要

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of snRNA transcription by RNA polymerase II and positive regulation of I-kappaB kinase/NF-kappaB signaling. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and intellectual disability. Orthologous to human CC2D1A (coiled-coil and C2 domain containing 1A). [provided by Alliance of Genome Resources, Apr 2022]