1. Gene
  2. Zbtb16 - zinc finger and BTB domain containing 16 Gene

Zbtb16 - zinc finger and BTB domain containing 16 Gene

种属: Rattus norvegicus

同用名: Lx; Plzf; Zfp145; Znf145

基因 ID: 353227 | 基因类型: protein coding

关于 Zbtb16

功能概要

Enables several functions, including DNA-binding transcription factor activity; double-stranded DNA binding activity; and protein C-terminus binding activity. Involved in embryonic limb morphogenesis; ossification involved in bone maturation; and protein localization to nucleus. Located in cytosol; nucleus; and plasma membrane. Used to study caudal regression syndrome and polydactyly. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human ZBTB16 (zinc finger and BTB domain containing 16). [provided by Alliance of Genome Resources, Apr 2022]

Zbtb16 基因产物(1)

mRNA Protein Name
NM_001013181.1 NP_001013199.1 zinc finger and BTB domain-containing protein 16
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
14657020 RGD
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
14657020 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15925207 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
19191224 RGD
enables type 2 angiotensin receptor binding IPI
IPI: 通过物理相互作用推断
14657020 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in embryonic digit morphogenesis IMP
IMP: 通过突变表型推断
19191224 RGD
involved in embryonic hindlimb morphogenesis IMP
IMP: 通过突变表型推断
19191224 RGD
involved in ossification involved in bone maturation IMP
IMP: 通过突变表型推断
27727328 RGD
involved in protein localization to nucleus IDA
IDA: 通过直接分析推断
19191224 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

zinc finger and BTB domain-containing protein 16

Polydactyly-luxate syndrome

promyelocytic leukemia zinc finger

zinc finger and BTB domain containing 16 protein

zinc finger protein 145

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Zbtb16 NCBI NCBI:7704