2. Gene
  3. Slc25a12 - solute carrier family 25 member 12 Gene

Slc25a12 - solute carrier family 25 member 12 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Aralar1; RGD1561141

基因 ID: 362145 | 基因类型: protein coding

关于 Slc25a12

功能概要

Predicted to enable acidic amino acid transmembrane transporter activity; calcium ion binding activity; and identical protein binding activity. Involved in several processes, including malate-aspartate shuttle; positive regulation of ATP biosynthetic process; and regulation of glucose metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in Asperger syndrome; autistic disorder; and developmental and epileptic encephalopathy 39. Orthologous to human SLC25A12 (solute carrier family 25 member 12). [provided by Alliance of Genome Resources, Apr 2022]

Slc25a12 基因产物(1)

mRNA Protein Name
NM_001399269.1 NP_001386198.1 electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in glutamate biosynthetic process IMP
IMP: 通过突变表型推断
19764902 RGD
involved in malate-aspartate shuttle IMP
IMP: 通过突变表型推断
19764902 RGD
involved in negative regulation of glucose catabolic process to lactate via pyruvate IMP
IMP: 通过突变表型推断
19764902 RGD
involved in positive regulation of ATP biosynthetic process IMP
IMP: 通过突变表型推断
19764902 RGD
involved in positive regulation of glucose metabolic process IMP
IMP: 通过突变表型推断
19764902 RGD
involved in positive regulation of myelination IMP
IMP: 通过突变表型推断
20015484 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

calcium-binding mitochondrial carrier protein Aralar1

solute carrier family 25 (aspartate/glutamate carrier), member 12

solute carrier family 25 (mitochondrial carrier, Aralar), member 12

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13092 SLC25A12 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS20672 Slc25a12 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS27183 Slc25a12 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc25a12 NCBI NCBI:8604
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