2. Gene
  3. Rac1 - Rac family small GTPase 1 Gene

Rac1 - Rac family small GTPase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 363875 | 基因类型: protein coding

关于 Rac1

功能概要

Enables several functions, including GTP binding activity; Rho GDP-dissociation inhibitor binding activity; and enzyme binding activity. Involved in several processes, including Rac protein signal transduction; bone resorption; and regulation of cellular biosynthetic process. Located in several cellular components, including Golgi membrane; cytosol; and dendritic spine. Used to study congestive heart failure. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 48; colon adenocarcinoma; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1). [provided by Alliance of Genome Resources, Apr 2022]

Rac1 基因产物(1)

mRNA Protein Name
NM_134366.1 NP_599193.1 ras-related C3 botulinum toxin substrate 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATPase binding IPI
IPI: 通过物理相互作用推断
20671235 RGD
enables GTP binding IDA
IDA: 通过直接分析推断
12672819 RGD
enables GTPase activity IDA
IDA: 通过直接分析推断
12672819 RGD
enables Rho GDP-dissociation inhibitor binding IPI
IPI: 通过物理相互作用推断
22564631 RGD
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
22679019 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
15608632 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
20861382 RGD
enables small GTPase binding IPI
IPI: 通过物理相互作用推断
16040606 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in actin cytoskeleton organization IDA
IDA: 通过直接分析推断
10350213 RGD
involved in actin filament organization IMP
IMP: 通过突变表型推断
12413953 RGD
involved in bone resorption IDA
IDA: 通过直接分析推断
10350213 RGD
involved in cellular response to mechanical stimulus IDA
IDA: 通过直接分析推断
12105187 RGD
involved in chemotaxis IMP
IMP: 通过突变表型推断
11756405 RGD
involved in mast cell chemotaxis IMP
IMP: 通过突变表型推断
12413953 RGD
involved in positive regulation of DNA replication IMP
IMP: 通过突变表型推断
9487126 RGD
involved in positive regulation of filopodium assembly IMP
IMP: 通过突变表型推断
15788770 RGD
involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
IMP: 通过突变表型推断
23412604 RGD
involved in positive regulation of lamellipodium assembly IMP
IMP: 通过突变表型推断
12105187 RGD
involved in postsynaptic actin cytoskeleton organization EXP
EXP: 通过实验结果推断
25284783 RGD
involved in postsynaptic actin cytoskeleton organization IDA
IDA: 通过直接分析推断
25284783 RGD
involved in postsynaptic actin cytoskeleton organization IMP
IMP: 通过突变表型推断
25284783 RGD
involved in regulation of nitric oxide biosynthetic process IGI
IGI: 通过遗传相互作用推断
16055727 RGD
involved in semaphorin-plexin signaling pathway IMP
IMP: 通过突变表型推断
20696765 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in GABA-ergic synapse EXP
EXP: 通过实验结果推断
25284783 RGD
is active in GABA-ergic synapse IDA
IDA: 通过直接分析推断
25284783 RGD
is active in GABA-ergic synapse IMP
IMP: 通过突变表型推断
25284783 RGD
located in Golgi membrane IDA
IDA: 通过直接分析推断
15147909 RGD
located in cytosol IDA
IDA: 通过直接分析推断
20696765 RGD
located in membrane IDA
IDA: 通过直接分析推断
20696765 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

ras-related C3 botulinum toxin substrate 1

p21-Rac1

ras-related C3 botulinum toxin substrate 1 (rho family small GTP binding protein Rac1)

rho family, small GTP binding protein Rac1

相关产品

Clinical Phase
生物活性分子 (1)
目录号 产品名 作用方式
纯度 Phase
HY-112842 MBQ-167 Inhibitor 99.64% Phase 1
Pre-clinical Phase
生物活性分子 (76)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-18723 Yoda 1 99.97% 否
HY-15723A NSC 23766 trihydrochloride 99.41% 否
HY-12755 ML141 99.96% 否
HY-12646 Rhosin hydrochloride 99.94% 否
HY-16659 EHT 1864 Inhibitor 99.85% 否
HY-12810 EHop-016 Inhibitor 99.85% 否
HY-100047 Nα,Nα-Bis(carboxymethyl)-L-lysine 98.80% 否
HY-125792 Nexinhib20 Inhibitor 99.86% 否
HY-124306 ML-099 Activator 99.75% 否
HY-104064 1A-116 99.72% 否
HY-110100 CPYPP Inhibitor 98.51% 否
HY-118208 ML-097 Inhibitor 99.90% 否
HY-115376 Z62954982 Inhibitor 99.38% 否
HY-12646A Rhosin 95.08% 否
HY-N0710 alpha-Cyperone 99.68% 否
HY-U00145 Digeranyl bisphosphonate Inhibitor 99.07% 否
HY-113849 MLS-573151 Inhibitor 99.70% 否
HY-136383 AZA1 98.17% 否
HY-B0580B (R)-Ketorolac Inhibitor 99.65% 否
HY-102078 ZINC69391 99.76% 否
HY-119576 Phox-I2 Inhibitor 99.44% 否
HY-112307A (Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol sodium 99.97% 否
HY-107501 (Rac)-1-Oleoyl lysophosphatidic acid sodium Control 98.0% 否
HY-158304 Rac1-IN-4 Inhibitor 98.61% 否
HY-133146 DJ001 Inhibitor 99.92% 否
HY-15031 l-Naproxen Inhibitor 99.63% 否
HY-120213 YH-306 98.34% 否
HY-156668 Rac1-IN-3 Inhibitor 98.28% 否
HY-P1382A Rac1 Inhibitor W56 TFA Inhibitor 99.92% 否
HY-175341 Rac1-IN-5 Inhibitor 99.84% 否
HY-50733A CX-5011 99.48% 否
HY-RS11591 RAC1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W127391 1,2-Dilaurin 98.0% 否
HY-P10038A mP6 TFA Inhibitor 98.48% 否
HY-131598C 6-Thio-GTP tetrasodium Inhibitor 99.7% 否
HY-143699S (Rac)-1,2-Bis-palmitol-3-chloropropanediol-d5 97.62% 否
HY-152095 PPI-GIT1/β-Pix PPI-IN-1 Inhibitor 99.01% 否
HY-W013060 (Rac)-1,2-Dilinoleoyl-3-palmitoyl-glycerol 99.0% 否
HY-W127550 1,2-Dipalmitoyl-sn-glycero-3-phospho-rac-(1-glycerol) sodium / 否
HY-50733 CX-5011 free base / 否
HY-115507 NMac1 / 否
HY-109541S6 (Rac)-Colfosceril miristate-d72 / 否
HY-120229 GGTI-2147 Inhibitor / 否
HY-137862A (Rac)-1-Oleoyl lysophosphatidic acid Control / 否
HY-147076 20:4 PG sodium / 否
HY-170458 18:0-18:2 PG sodium / 否
HY-172917 Rho GTPase inhibitor 1 Inhibitor / 否
HY-E70632 PIP5K1B Recombinant Human Active Lipid Kinase / 否
HY-P10038 mP6 Inhibitor / 否
HY-P10107 TAT-PAK18 R192A Control / 否
HY-P11092 TLQP-62 (mouse,rat) / 否
HY-P1382 Rac1 Inhibitor W56 Inhibitor / 否
HY-P1383A Rac1 Inhibitor F56, control peptide TFA Inhibitor / 否
HY-RS12018 RNASE1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-W127356 (Rac)-1,2-Distearoyl-3-chloropropanediol-d5 / 否
HY-W127363 (Rac)-1,2-Dihexadecylglycerol / 否
HY-W127415 rac-1-Stearoyl-3-chloropropanediol / 否
HY-W127415S (Rac)-1-Stearoyl-3-chloropropanediol-d5 / 否
HY-W127570 rac-1,2-Distearoyl-3-chloropropanediol / 否
HY-W587715S (Rac)-1,2-Dioleoyl-3-chloropropanediol-d5 / 否
HY-W653931 rac 1,2-Bis-palmitoyl-3-chloropropanediol-13C3 / 否
HY-W767222 rac-1-Linoleoyl-2-chloropropanediol-d5 / 否
HY-W767223 rac 1-Palmitoyl-2-chloropropanediol-d5 / 否
HY-W770200 rac 1-Oleoyl-2,3-isopropylidieneglycerol-d5 / 否
HY-W777103 (Rac)-1-Oleoyl-3-linoleoyl-glycerol / 否
HY-W777682 (Rac)-1-Linoleoyl-2,3-isopropylidene-glycerol / 否
HY-W777871 rac-1-Palmitoyl-2-linoleoyl-3-chloropropanediol-d5 / 否
HY-134243 6-T-GDP Inhibitor / 否
HY-RS16742 Rac1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23179 Rac1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W702728 rac 1-Palmitoyl-2-chloropropanediol / 否
HY-W749756 rac-1,2-Distearoyl-3-chloropropanediol-13C3 / 否
HY-W766801 rac-1-Linoleoyl-3-chloropropanediol-d5 / 否
HY-W766807 rac-1,2-Dilinoleoyl-3-chloropropanediol-d5 / 否
HY-W766831 rac 1-oleoyl-2-linoleoyl-3-chloropropanediol-d5 / 否
HY-W777866 (Rac)-1-Linoleoyl-2-stearoyl-3-chloropropanediol / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rac1 NCBI NCBI:5879
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