2. Gene
  3. HRNR - hornerin Gene

HRNR - hornerin Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：角蛋白

种属: Homo sapiens

同用名: FLG3; S100A16; S100a18

基因 ID: 388697 | 基因类型: protein coding

关于 HRNR

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:152,212,076-152,224,193 (from NCBI)

This gene has 1 transcript (splice variant), 39 orthologues and 3 paralogues. Low expression observed in reference dataset.

功能概要

预测具有钙离子结合活性和过渡金属离子结合活性。参与细胞包膜组织和皮肤屏障的建立。位于角化信封中；透明角质颗粒；和细胞质的核周区。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable calcium ion binding activity and transition metal ion binding activity. Involved in cell envelope organization and establishment of skin barrier. Located in cornified envelope; keratohyalin granule; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

HRNR 基因产物(1)

mRNA Protein Name
NM_001009931.3 NP_001009931.1 hornerin
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell envelope organization IDA
IDA: 通过直接分析推断
21282207 GOA
involved in establishment of skin barrier IEP
IEP: 通过表达模式推断
23403047 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cornified envelope IDA
IDA: 通过直接分析推断
21282207 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
21282207 GOA
located in keratohyalin granule IDA
IDA: 通过直接分析推断
21282207 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
21282207 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HRNR 蛋白结构

S_100

S_100: S-100/ICaBP type calcium binding domain (4 - 47)

  • 0
  • 500
  • 1000
  • 1500
  • 2000
  • 2500
  • 2850 a.a.
蛋白主名 其他名称

hornerin

filaggrin family member 3

关联疾病

疾病名称 别名
Ichthyosis Vulgaris

Ichthyosis Simplex

Dominant Congenital Ichthyosiform Erythroderma

Common Ichthyosis

Fish Scale Disease

VI

Ichthyoses

Congenital Ichthyosis
Autosomal Recessive Congenital Ichthyosis

Lamellar Ichthyosis

Congenital Ichthyosiform Erythroderma

Li

Congenital Nonbullous Ichthyosiform Erythroderma

Arci

Congenital Lamellar Ichthyosis

Nonbullous Congenital Ichthyosiform Erythroderma

Cie

Congenital Non-Bullous Ichthyosiform Erythroderma

Erythrodermic Ichthyosis

Nbcie

Ncie

Non-Bullous Congenital Ichthyosiform Erythroderma

Collodion Baby

Ichthyosis, Lamellar

Non Bullous Congenital Ichthyosiform Erythroderma

Ichthyosiform Erythroderma, Brocq Congenital, Nonbullous Form

Ichthyosiform Erythroderma, Congenital, Nonbullous, 1

Collodion Baby Syndrome

Ichthyoses, Lamellar

Nbie

Nonbullous Ichthyosiform Erythroderma

Classic Lamellar Ichthyosis

Ichthyosiform Erythroderma Nonbullous Congenital

Ichthyosiform Erythroderma Congenital

Ichthyosis, Congenital, Autosomal Recessive

Ichthyosiform Erythroderma, Congenital

Collodion Fetus

Non-Bullous Ichthyosiform Erythroderma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06372 HRNR Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus HRNR RGD RGD:1307660
Mus musculus HRNR MGD MGI:3046938
Felis catus HRNR VGNC VGNC:107561
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z