NDUFB2 - NADH:ubiquinone oxidoreductase subunit B2 Gene

中文名称：NADH：泛醌氧化还原酶亚基 B2

种属: Homo sapiens

同用名: AGGG; CI-AGGG

关于 NDUFB2

功能概要

该基因编码的蛋白质是多亚基 NADH 的一个亚基：泛醌氧化还原酶 (复合物 I) 。哺乳动物复合体 I 由 45 个不同的亚基组成。该蛋白具有 NADH 脱氢酶活性和氧化还原酶活性。它在将电子从 NADH 转移到呼吸链中起着重要作用。该酶的直接电子受体被认为是泛醌。亲水分析表明，该亚基和其他 4 个亚基具有整体亲水模式，即使它们存在于复合物 I 的疏水蛋白 (HP) 部分中。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 Other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I. [provided by RefSeq, Jul 2008]