OVGP1 - oviductal glycoprotein 1 Gene

中文名称：输卵管糖蛋白 1

种属: Homo sapiens

同用名: EGP; OGP; MUC9; CHIT5

关于 OVGP1

功能概要

该基因编码一种大的、富含碳水化合物的上皮糖蛋白，在苏氨酸、丝氨酸和富含脯氨酸的串联重复序列中有许多 O-糖基化位点。该基因类似于粘蛋白和糖基水解酶 18 个基因家族的成员。表达调节可能是雌激素依赖性的。基因表达和蛋白质分泌发生在晚期卵泡发育到早期卵裂期胚胎发育过程中。该蛋白由无纤毛的输卵管上皮细胞分泌，并与排卵卵母细胞、卵裂球和精子顶体区域相关。[RefSeq 提供，2008 年 7 月]

This gene encodes a large, carbohydrate-rich, epithelial glycoprotein with numerous O-glycosylation sites located within threonine, serine, and proline-rich tandem repeats. The gene is similar to members of the Mucin and the glycosyl hydrolase 18 gene families. Regulation of expression may be estrogen-dependent. Gene expression and protein secretion occur during late follicular development through early cleavage-stage embryonic development. The protein is secreted from non-ciliated oviductal epithelial cells and associates with ovulated oocytes, blastomeres, and spermatozoan acrosomal regions. [provided by RefSeq, Jul 2008]