2. Gene
  3. PHF11 - PHD finger protein 11 Gene

PHF11 - PHD finger protein 11 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：PHD 指蛋白 11

种属: Homo sapiens

同用名: APY; BCAP; IGEL; IGER; IGHER; NYREN34; NY-REN-34

基因 ID: 51131 | 基因类型: protein coding

关于 PHF11

Cytogenetic location: 13q14.2 Genomic coordinates (GRCh38): 13:49,495,953-49,528,992 (from NCBI)

This gene has 18 transcripts (splice variants), 133 orthologues and 3 paralogues. Ubiquitous expression in lymph node (RPKM 13.0), spleen (RPKM 12.7) and 25 other tissues.

功能概要

该基因编码的蛋白质含有 PHD (植物同源结构域) 型锌指。该基因已在一些研究中被确定为哮喘的候选基因。自然发生的通读转录可能从上游 SETDB2 (SET 结构域分叉 2) 基因到该位点发生。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 3 月]

This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

PHF11 基因产物(2)

mRNA Protein Name
NM_001040443.3 NP_001035533.1 PHD finger protein 11 isoform a
NM_001040444.2 NP_001035534.1 PHD finger protein 11 isoform b
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

PHF11 蛋白结构

zf-HC5HC2H

zf-HC5HC2H: PHD-like zinc-binding domain (68 - 160)

  • 0
  • 100
  • 200
  • 300
  • 331 a.a.
蛋白主名 其他名称

PHD finger protein 11

BRCA1 C-terminus-associated protein

关联疾病

疾病名称 别名
Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus
Near-Fatal Asthma
Ige Responsiveness, Atopic

ATOPY

Atopy, Susceptibility To

Ige, Elevated Level Of

IGER

Immunoglobulin E, Basic Level Of, In Serum

Ige, Level Of

Igel

Ige Response Underlying Allergic Asthma And Rhinitis

Atopic Hypersensitivity

Immediate Hypersensitivity
Dermatitis, Atopic

Atopic Dermatitis

Atopic Eczema

Dermatitis, Atopic, Susceptibility To, 1

Atod

Eczema, Atopic

Dermatitis, Atopic 1

Allergic Dermatitis

Atopic Neurodermatitis

Besnier'S Prurigo

Dermatitis, Atopic, 1

Dermatitis Atopic

Eczema

Besnier Prurigo
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10415 PHF11 Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus PHF11 VGNC VGNC:104698
Bos taurus PHF11 VGNC VGNC:106864
Canis familiaris PHF11 VGNC VGNC:44481
Rattus norvegicus PHF11 RGD RGD:1310853
Macaca mulatta PHF11 VGNC VGNC:75814
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z