2. Gene
  3. ACP6 - acid phosphatase 6, lysophosphatidic Gene

ACP6 - acid phosphatase 6, lysophosphatidic Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：酸性磷酸酶 6，溶血磷脂

种属: Homo sapiens

同用名: LPAP; ACPL1; PACPL1

基因 ID: 51205 | 基因类型: protein coding

关于 ACP6

Cytogenetic location: 1q21.2 Genomic coordinates (GRCh38): 1:147,629,658-147,670,524 (from NCBI)

This gene has 10 transcripts (splice variants), 220 orthologues and 5 paralogues. Ubiquitous expression in thyroid (RPKM 3.4), prostate (RPKM 3.3) and 25 other tissues.

功能概要

该基因编码组氨酸酸性磷酸酶蛋白家族的一个成员。编码的蛋白质水解溶血磷脂酸，后者参与 G 蛋白偶联受体信号传导、脂筏调节和细胞内脂质成分的平衡。可变剪接导致多个转录本变体。[RefSeq 提供，2016 年 5 月]

This gene encodes a member of the histidine Acid Phosphatase protein family. The encoded protein hydrolyzes lysophosphatidic acid, which is involved in G protein-coupled receptor signaling, lipid raft modulation, and in balancing lipid composition within the cell. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2016]

ACP6 基因产物(2)

mRNA Protein Name
NM_001323625.2 NP_001310554.1 lysophosphatidic acid phosphatase type 6 isoform 2
NM_016361.5 NP_057445.4 lysophosphatidic acid phosphatase type 6 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lysophosphatidic acid phosphatase activity IDA
IDA: 通过直接分析推断
10506173 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in lysobisphosphatidic acid metabolic process IDA
IDA: 通过直接分析推断
23807634 GOA
involved in phospholipid metabolic process IMP
IMP: 通过突变表型推断
10506173 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12010880 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
10506173 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ACP6 蛋白结构

His_Phos_2

His_Phos_2: Histidine phosphatase superfamily (branch 2) (49 - 379)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 428 a.a.
蛋白主名 其他名称

lysophosphatidic acid phosphatase type 6

acid phosphatase-like protein 1

关联疾病

疾病名称 别名
Chromosome 1q21.1 Deletion Syndrome, 1.35-Mb

Chromosome 1q21.1 Deletion Syndrome

1q21.1 Microdeletion Syndrome

Monosomy 1q21.1

1q21.1 Microdeletion

Chromosome 1q21.1 Microdeletion Syndrome

1q21.1 Contiguous Gene Deletion

1q21.1 Deletion

Del(1)(Q21)

1q21.1 Deletion Syndrome
Duodenal Atresia

Duodenal Stenosis

Familial Duodenal Atresia
Chromosome 1p36 Deletion Syndrome

1p36 Deletion Syndrome

Deletion 1p36

Monosomy 1p36

Subtelomeric 1p36 Deletion

Monosomy 1p36 Syndrome

Distal Monosomy 1p36

Del(1)(P36)

Deletion 1pter

Monosomy 1pter
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00191 ACP6 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22095 Acp6 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28615 Acp6 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus ACP6 VGNC VGNC:59527
Mus musculus ACP6 MGD MGI:1931010
Bos taurus ACP6 VGNC VGNC:52602
Rattus norvegicus ACP6 RGD RGD:1306336
Macaca mulatta ACP6 VGNC VGNC:69548
Canis familiaris ACP6 VGNC VGNC:54914
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z