1. Gene
  2. Abcb10 - ATP-binding cassette, sub-family B (MDR/TAP), member 10 Gene

Abcb10 - ATP-binding cassette, sub-family B (MDR/TAP), member 10 Gene

种属: Mus musculus

同用名: Abc-me; Abcb12

基因 ID: 56199 | 基因类型: protein coding

关于 Abcb10

功能概要

This gene encodes a member of the ATP-binding cassette superfamily of transporters. ATP-binding cassette proteins transport various molecules across extra- and intra-cellular membranes. The encoded protein is localized to the mitochondrial inner membrane where it interacts with and stabilizes mitoferrin-1, and is important for heme biosynthesis. Additional evidence suggests the encoded protein is involved in oxidative stress protection and erythropoisesis. [provided by RefSeq, May 2013]

Abcb10 基因产物(1)

mRNA Protein Name
NM_019552.2 NP_062425.1 ATP-binding cassette sub-family B member 10, mitochondrial precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP binding IDA
IDA: 通过直接分析推断
26053025 MGI
enables ATP hydrolysis activity IDA
IDA: 通过直接分析推断
33253225 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
15215243 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
19805291 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heme biosynthetic process IMP
IMP: 通过突变表型推断
24421385 MGI
involved in positive regulation of erythrocyte differentiation IMP
IMP: 通过突变表型推断
22240895 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
10835348 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
15215243 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ATP-binding cassette sub-family B member 10, mitochondrial

ABC-mitochondrial erythroid protein

ATP-binding cassette transporter 10

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Abcb10 NCBI NCBI:23456