Huwe1 - HECT, UBA and WWE domain containing 1 Gene

种属: Mus musculus

同用名: Mule; Ib772; LASU1; Ureb1; Gm1718; Arf-bp1; 5430439H10Rik; C430014N20Rik

关于 Huwe1

功能概要

Predicted to enable DNA binding activity and ubiquitin protein Ligase activity. Involved in circadian regulation of gene expression and positive regulation of protein ubiquitination. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in Golgi membrane and nucleus. Is expressed in several structures, including extraembryonic component. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Turner type. Orthologous to human HUWE1 (HECT, UBA and WWE domain containing E3 ubiquitin protein Ligase 1). [provided by Alliance of Genome Resources, Apr 2022]