1. Gene
  2. MBL2 - Mbl2 mannose binding lectin 2 Gene

MBL2 - Mbl2 mannose binding lectin 2 Gene

种属: Rattus norvegicus

同用名: Ab2-001; Ab2-011

基因 ID: 64668 | 基因类型: protein coding

关于 MBL2

功能概要

Enables several functions, including identical protein binding activity; monosaccharide binding activity; and phosphatidylinositol-4-phosphate binding activity. Involved in positive regulation of complement activation and positive regulation of protein processing. Located in extracellular space. Part of protein-containing complex. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); Bacterial infectious disease (multiple); Fungal infectious disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MBL2 (mannose binding lectin 2). [provided by Alliance of Genome Resources, Apr 2022]

MBL2 基因产物(1)

mRNA Protein Name
NM_022704.2 NP_073195.2 mannose-binding protein C precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables D-mannose binding IDA
IDA: 通过直接分析推断
10589993 RGD
enables calcium ion binding IDA
IDA: 通过直接分析推断
9922166 RGD
enables galactose binding IDA
IDA: 通过直接分析推断
8557671 RGD
enables identical protein binding IDA
IDA: 通过直接分析推断
8557671 RGD
enables identical protein binding IPI
IPI: 通过物理相互作用推断
9230118 RGD
enables phosphatidylinositol-4-phosphate binding IDA
IDA: 通过直接分析推断
9315725 RGD
enables protease binding IPI
IPI: 通过物理相互作用推断
11337510 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of complement activation IDA
IDA: 通过直接分析推断
9920905 RGD
involved in positive regulation of protein processing IDA
IDA: 通过直接分析推断
20118239 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
3124748 RGD
part of protein-containing complex IMP
IMP: 通过突变表型推断
9920905 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

mannose-binding protein C

MBP-C

RA-reactive factor P28A subunit

RARF/P28A

mannan-binding protein

mannose binding lectin 2 (protein C)

mannose-binding lectin (protein C) 2

mannose-binding protein C (liver)

mannose-binding protein C-like

ra-reactive factor polysaccharide-bin

直系同源

种属 基因名 来源 基因 ID
Homo sapiens MBL2 NCBI NCBI:4153
Mus musculus MBL2 NCBI NCBI:17195