2. Gene
  3. SOX15 - SRY-box transcription factor 15 Gene

SOX15 - SRY-box transcription factor 15 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：SRY-box 转录因子 15

种属: Homo sapiens

同用名: SOX20; SOX26; SOX27

基因 ID: 6665 | 基因类型: protein coding

关于 SOX15

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,588,178-7,590,094 (from NCBI)

This gene has 3 transcripts (splice variants), 281 orthologues and 20 paralogues. Biased expression in skin (RPKM 12.3), esophagus (RPKM 6.9) and 8 other tissues.

功能概要

该基因编码参与胚胎发育调控和细胞命运决定的转录因子 SOX (SRY 相关 HMG 盒) 家族成员。编码的蛋白质在与其他蛋白质形成蛋白质复合物后可以充当转录调节剂。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with Other proteins. [provided by RefSeq, Jul 2008]

SOX15 基因产物(1)

mRNA Protein Name
NM_006942.2 NP_008873.1 protein SOX-15
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SOX15 蛋白结构

HMG_box

HMG_box: HMG (high mobility group) box (49 - 117)

  • 0
  • 100
  • 200
  • 233 a.a.
蛋白主名 其他名称

protein SOX-15

SRY (sex determining region Y)-box 15

关联疾病

疾病名称 别名
Acromesomelic Dysplasia 2a

Chondrodysplasia, Grebe Type

Acromesomelic Dysplasia, Grebe Type

Grebe Chondrodysplasia

Amdg

Grebe Syndrome

AMD2A

Grebe Dysplasia

Achondrogenesis, Brazilian

Achondrogenesis, Type Ii, Formerly

Acromesomelic Dysplasia-2a

Achondrogenesis Type Ii

Brazilian Achondrogenesis

Acromesomelic Chondrodysplasia, Grebe Type
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13588 SOX15 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22815 Sox15 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29330 Sox15 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus SOX15 MGD MGI:98363
Macaca mulatta SOX15 VGNC VGNC:104658
Bos taurus SOX15 VGNC VGNC:35143
Felis catus SOX15 VGNC VGNC:65580
Rattus norvegicus SOX15 RGD RGD:1312022
Canis familiaris SOX15 VGNC VGNC:46675
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