1. Gene
  2. Uba5 - ubiquitin-like modifier activating enzyme 5 Gene

Uba5 - ubiquitin-like modifier activating enzyme 5 Gene

种属: Mus musculus

同用名: Ube1dc1; 5730525G14Rik

基因 ID: 66663 | 基因类型: protein coding

关于 Uba5

功能概要

Enables UFM1 activating enzyme activity. Involved in erythrocyte differentiation; megakaryocyte differentiation; and protein ufmylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in cytosol. Is expressed in liver. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 24 and developmental and epileptic encephalopathy 44. Orthologous to human UBA5 (ubiquitin like modifier activating enzyme 5). [provided by Alliance of Genome Resources, Apr 2022]

Uba5 基因产物(1)

mRNA Protein Name
NM_025692.3 NP_079968.2 ubiquitin-like modifier-activating enzyme 5
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables UFM1 activating enzyme activity IDA
IDA: 通过直接分析推断
21304510 MGI
enables UFM1 activating enzyme activity IMP
IMP: 通过突变表型推断
20018847 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
21304510 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in erythrocyte differentiation IMP
IMP: 通过突变表型推断
21304510 MGI
involved in megakaryocyte differentiation IMP
IMP: 通过突变表型推断
21304510 MGI
involved in protein ufmylation IDA
IDA: 通过直接分析推断
20018847 MGI
involved in protein ufmylation IMP
IMP: 通过突变表型推断
33372156 MGI
involved in regulation of type II interferon production IMP
IMP: 通过突变表型推断
33372156 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

ubiquitin-like modifier-activating enzyme 5

UFM1-activating enzyme

ubiquitin-activating enzyme 5

ubiquitin-activating enzyme E1 domain-containing protein 1

ubiquitin-activating enzyme E1-domain containing 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Uba5 NCBI NCBI:79876