2. Gene
  3. Rtf1 - RTF1, Paf1/RNA polymerase II complex component Gene

Rtf1 - RTF1, Paf1/RNA polymerase II complex component Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Gtl7; cbp82; 2900005O08Rik; 6530416A09Rik

基因 ID: 76246 | 基因类型: protein coding

关于 Rtf1

功能概要

Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity and single-stranded DNA binding activity. Involved in several processes, including endodermal cell fate commitment; histone H3-K4 trimethylation; and positive regulation of histone H3-K4 methylation. Acts upstream of or within blastocyst growth. Located in nucleolus. Part of Cdc73/Paf1 complex. Is expressed in several structures, including brain and retina nuclear layer. Orthologous to human RTF1 (RTF1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Apr 2022]

Rtf1 基因产物(1)

mRNA Protein Name
NM_030112.2 NP_084388.2 RNA polymerase-associated protein RTF1 homolog precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to protein binding IPI
IPI: 通过物理相互作用推断
27749823 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within blastocyst growth IMP
IMP: 通过突变表型推断
24036311 MGI
involved in chromatin organization IMP
IMP: 通过突变表型推断
19345177 MGI
involved in endodermal cell fate commitment IMP
IMP: 通过突变表型推断
19345177 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
19345177 MGI
involved in stem cell population maintenance IMP
IMP: 通过突变表型推断
19345177 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Cdc73/Paf1 complex IPI
IPI: 通过物理相互作用推断
27749823 MGI
located in nucleolus IDA
IDA: 通过直接分析推断
9701556 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

RNA polymerase-associated protein RTF1 homolog

Rtf1, Paf1/RNA polymerase II complex component, homolog

gene trap locus 7

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12318 RTF1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22315 Rtf1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28837 Rtf1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rtf1 NCBI NCBI:23168
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