2. Gene
  3. ZNF142 - zinc finger protein 142 Gene

ZNF142 - zinc finger protein 142 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：锌指蛋白 142

种属: Homo sapiens

同用名: HA4654; pHZ-49; NEDISHM

基因 ID: 7701 | 基因类型: protein coding

关于 ZNF142

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:218,633,329-218,659,623 (from NCBI)

This gene has 6 transcripts (splice variants), 136 orthologues, 36 paralogues and is associated with 2 phenotypes. Ubiquitous expression in brain (RPKM 3.6), testis (RPKM 3.6) and 25 other tissues.

功能概要

该基因编码的蛋白质属于 C2H2 型锌指蛋白的 Kruppel 家族。它含有 31 个 C2H2 型锌指，可能参与转录调控。已发现该基因的可变剪接转录物变体。[RefSeq 提供，2013 年 1 月]

The protein encoded by this gene belongs to the Kruppel family of C2H2-type zinc finger proteins. It contains 31 C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2013]

ZNF142 基因产物(14)

mRNA Protein Name
NM_001105537.4 NP_001099007.1 zinc finger protein 142 isoform 1
NM_001366287.2 NP_001353216.1 zinc finger protein 142 isoform 2
NM_001366288.2 NP_001353217.1 zinc finger protein 142 isoform 2
NM_001366289.2 NP_001353218.1 zinc finger protein 142 isoform 2
NM_001366290.3 NP_001353219.1 zinc finger protein 142 isoform 3
NM_001366291.2 NP_001353220.1 zinc finger protein 142 isoform 1
NM_001367339.1 NP_001354268.1 zinc finger protein 142 isoform 4
NM_001367340.1 NP_001354269.1 zinc finger protein 142 isoform 4
NM_001367341.1 NP_001354270.1 zinc finger protein 142 isoform 4
NM_001367342.1 NP_001354271.1 zinc finger protein 142 isoform 4
NM_001379659.1 NP_001366588.1 zinc finger protein 142 isoform 3
NM_001379660.1 NP_001366589.1 zinc finger protein 142 isoform 3
NM_001379661.1 NP_001366590.1 zinc finger protein 142 isoform 3
NM_001379662.1 NP_001366591.1 zinc finger protein 142 isoform 1

ZNF142 蛋白结构

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (192 - 211)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (253 - 275)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (416 - 437)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (457 - 479)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (514 - 536)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (836 - 857)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (868 - 887)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (1136 - 1159)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (1187 - 1210)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (1229 - 1251)

zf-C2H2_4

zf-C2H2_4: C2H2-type zinc finger (1286 - 1309)

zf-H2C2_5

zf-H2C2_5: C2H2-type zinc-finger domain (1380 - 1403)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (1469 - 1489)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (1495 - 1518)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (1523 - 1545)

zf-C2H2

zf-C2H2: Zinc finger, C2H2 type (1565 - 1587)

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  • 1687 a.a.
蛋白主名 其他名称

zinc finger protein 142

zinc finger protein 142 (clone pHZ-49)

关联疾病

疾病名称 别名
Neurodevelopmental Disorder With Impaired Speech And Hyperkinetic Movements

NEDISHM
Pancreatic Squamous Cell Carcinoma
Generalized Epilepsy With Febrile Seizures Plus, Type 7

Febrile Seizures, Familial, 3b

GEFSP7

GEFS+7

Generalized Epilepsy With Febrile Seizures Plus 7

Gefs+, Type 7

Generalised Epilepsy With Febrile Seizures Plus 7

Generalised Epilepsy With Febrile Seizures Plus Type 7

Generalized Epilepsy With Febrile Seizures Plus Type 7

FEB3B

Familial Febrile Convulsions 3

Gefs+ Type 7

Epilepsy, Generalized, With Febrile Seizures Plus, Type 7

Generalized Epilepsy With Febrile Seizures Plus, 7
Dystonia

Dystonic Disease

Dystonic Disorder

Dystonia Disorders

Neuroleptic Dyskinesia
Spastic Paraplegia 48, Autosomal Recessive

SPG48

Hereditary Spastic Paraplegia 48

Autosomal Recessive Spastic Paraplegia Type 48

Autosomal Recessive Spastic Paraplegia 48

Paraplegia, Spastic, Type 48, Autosomal Recessive
Cerebral Creatine Deficiency Syndrome

Deficiency, Cerebral Creatine, Syndrome
Cockayne Syndrome A

Cockayne Syndrome Type 1

Cockayne Syndrome, Type A

Cockayne Syndrome Type I

CSA

Cockayne Syndrome Classic Form

Cockayne Syndrome Classical

Cockayne Syndrome Type A

Ckn1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS16102 ZNF142 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ZNF142 RGD RGD:1309648
Mus musculus ZNF142 MGD MGI:1924514
Macaca mulatta ZNF142 VGNC VGNC:78844
Canis familiaris ZNF142 VGNC VGNC:48660
Bos taurus ZNF142 VGNC VGNC:37211
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