2. Gene
  3. NAA40 - N-alpha-acetyltransferase 40, NatD catalytic subunit Gene

NAA40 - N-alpha-acetyltransferase 40, NatD catalytic subunit Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：N-α-乙酰转移酶 40，NatD 催化亚基

种属: Homo sapiens

同用名: NatD; NAT11; PATT1; hNatD

基因 ID: 79829 | 基因类型: protein coding

关于 NAA40

Cytogenetic location: 11q13.1 Genomic coordinates (GRCh38): 11:63,939,002-63,957,319 (from NCBI)

This gene has 10 transcripts (splice variants) and 209 orthologues. Ubiquitous expression in testis (RPKM 9.3), spleen (RPKM 7.5) and 25 other tissues.

功能概要

启用 H2A 组蛋白乙酰转移酶活性； H4 组蛋白乙酰转移酶活性；和肽-丝氨酸-N-乙酰转移酶活性。参与 N 端蛋白质氨基酸乙酰化；组蛋白 H2A 乙酰化；和组蛋白 H4 乙酰化。位于中心卫星；胞质溶胶；和核质。 [由基因组资源联盟提供，2022 年 4 月]

Enables H2A Histone Acetyltransferase activity; H4 Histone Acetyltransferase activity; and peptide-serine-N-acetyltransferase activity. Involved in N-terminal protein amino acid acetylation; histone H2A acetylation; and histone H4 acetylation. Located in centriolar satellite; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

NAA40 基因产物(2)

mRNA Protein Name
NM_001300800.1 NP_001287729.1 N-alpha-acetyltransferase 40 isoform 2
NM_024771.4 NP_079047.2 N-alpha-acetyltransferase 40 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables histone H2A acetyltransferase activity IDA
IDA: 通过直接分析推断
25619998 GOA
enables histone H4 acetyltransferase activity IDA
IDA: 通过直接分析推断
25619998 GOA
enables peptide-serine-alpha-N-acetyltransferase activity IDA
IDA: 通过直接分析推断
25619998 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25619998 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

NAA40 蛋白结构

Acetyltransf_1

Acetyltransf_1: Acetyltransferase (GNAT) family (118 - 190)

  • 0
  • 100
  • 200
  • 237 a.a.
蛋白主名 其他名称

N-alpha-acetyltransferase 40

N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog

关联疾病

疾病名称 别名
Pulmonary Subvalvular Stenosis

Pulmonary Infundibular Stenosis

Congenital Infundibular Stenosis

Infundibular Pulmonic Stenosis

Infundibular Pulmonic Stenosis, Congenital

Subvalvular Pulmonic Stenosis
Microphthalmia, Syndromic 1

MCOPS1

Lenz Microphthalmia Syndrome

Lenz Dysplasia

Mcops4

Syndromic Microphthalmia 1

Lenz Microphthalmia

Maa

Microphthalmia Or Anophthalmos With Associated Anomalies

Syndromic Microphthalmia Type 4

Microphthalmia, Syndromic 4

Microphthalmia, Syndromic 4, Formerly

Mcops4, Formerly

Anop1, Formerly

Maa, Formerly

Lenz Type Microphthalmia

Syndromic Microphthalmia 4

Microphthalmia Lenz Type

Microphthalmia Syndromic 1

Syndromic Microphthalmia Type 1

Microphthalmia Syndromic 4

Microphthalmia With Ankyloblepharon And Intellectual Disability

Microphthalmia, Lenz Type

Microphthalmia-Ankyloblepharon-Intellectual Disability Syndrome

Microphthalmia, Syndromic, 1

Anop1

Microphthalmia, Syndromic, Type 1
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08990 NAA40 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS20996 Naa40 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS27513 Naa40 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus NAA40 VGNC VGNC:54619
Macaca mulatta NAA40 VGNC VGNC:96719
Canis familiaris NAA40 VGNC VGNC:51882
Felis catus NAA40 VGNC VGNC:81977
Rattus norvegicus NAA40 RGD RGD:1565838
Mus musculus NAA40 MGD MGI:1918249
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