BAALC - BAALC binder of MAP3K1 and KLF4 Gene

中文名称：MAP3K1 和 KLF4 的 BAALC 粘合因子

种属: Homo sapiens

基因 ID: 79870 | 基因类型: protein coding

关于 BAALC

Cytogenetic location: 8q22.3 Genomic coordinates (GRCh38): 8:103,140,725-103,230,305 (from NCBI)

This gene has 9 transcripts (splice variants) and 168 orthologues. Biased expression in brain (RPKM 101.5), adrenal (RPKM 7.1) and 1 other tissue.

功能概要

该基因是通过对急性髓性白血病 (AML) 患者的基因表达研究鉴定的。该基因在哺乳动物中是保守的，在低等生物中不存在。表达该基因的组织从神经外胚层发育而来。已针对该基因描述了编码不同蛋白质的多个选择性剪接转录变体；然而，一些转录变体仅在 AML 细胞系中发现。[RefSeq 提供，2008 年 7 月]

This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines. [provided by RefSeq, Jul 2008]

BAALC 基因产物(3)

mRNA	Protein	Name
NM_001024372.2	NP_001019543.1	brain and acute leukemia cytoplasmic protein isoform 2
NM_001364874.1	NP_001351803.1	brain and acute leukemia cytoplasmic protein isoform 3
NM_024812.3	NP_079088.1	brain and acute leukemia cytoplasmic protein isoform 1

基因本体论

分子功能
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytoplasm	IDA IDA: 通过直接分析推断	11707601	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

BAALC 蛋白结构

BAALC_N

0
100
180 a.a.

蛋白主名

其他名称

brain and acute leukemia cytoplasmic protein

BAALC, MAP3K1 and KLF4 binding

关联疾病

疾病名称

别名

Acute Leukemia

Stem Cell Leukaemia	Stem Cell Leukemia
Acute Leukemias	Acute Undifferentiated Leukemia
Undifferentiated Leukemia	Acute Leukaemia Of Unspecified Cell Type Without Mention Of Remission
Blast Cell Leukaemia	Blast Leukaemia
Blastic Leukaemia	Undifferentiated Leukaemia

Leukemia

Leukemias	Leukaemia, Unspecified, Without Mention Of Remission
Aleukemic Leukaemia	Chronic Leukaemia
Subacute Leukaemia	Leukaemia Disorder
Leukaemia Nos

Myeloid Leukemia

Myeloid Leukaemia	Leukaemia Myelogenous
Leukemia Myelogenous	Myeloid Granulocytic Leukaemia
Myeloid Granulocytic Leukemia	Non-Lymphocytic Leukemia
Leukemia, Myeloid	Granulocytic Leukaemia
Myelogenous Leukaemia	Myeloid Leukaemia, Unspecified, Without Mention Of Remission

Cleft Palate, Isolated

Cleft Palate	Isolated Cleft Palate
CPI	Cp
Palatoschisis	Cleft Palate Isolated
Uranostaphyloschisis	Congenital Fissure Of Palate
Cleft Of Secondary Palate

Leukemia, Acute Myeloid

Acute Myeloid Leukemia	Leukemia, Acute Myelogenous
Acute Myelogenous Leukemia	AML
Leukemia, Acute Myeloid, Susceptibility To	Acute Myeloblastic Leukemia
Leukemia, Acute Myeloid, Reduced Survival In, Somatic	Acute Myeloid Leukaemia
Leukemia, Myelocytic, Acute	Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome
Secondary Aml	Acute Myelocytic Leukemia
Acute Myeloid Leukemia, Somatic	Leukemia, Acute Myeloid, Somatic
Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic	Acute Myeloblastic Leukaemia
Acute Myelogenous Leukaemia	Aml - Acute Myeloid Leukemia
Acute Myeloid Leukemia With Cebpa Somatic Mutations	Aml With Cebpa Somatic Mutations
Inherited Acute Myeloid Leukemia	Familial Aml
Inherited Aml	Pure Familial Aml
Pure Familial Acute Myeloid Leukemia	Secondary Acute Myeloid Leukemia
Therapy-Related Aml And Myelodysplastic Syndrome	Acute Myeloid Leukemia, Secondary
Acute Non-Lymphoblastic Leukemia	Acute Non-Lymphocytic Leukemia
Acute Biphenotypic Leukemia	Acute Undifferentiated Leukemia
Acute Myeloblastic Leukaemia With Multilineage Dysplasia	Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission
Acute Myeloid Leukaemia With Myelodysplasia-Related Features

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS01329	BAALC Human Pre-designed siRNA Set A	Pre-designed Set	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	BAALC	VGNC	VGNC:26398
Mus musculus	BAALC	MGD	MGI:1928704
Canis familiaris	BAALC	VGNC	VGNC:38356
Rattus norvegicus	BAALC	RGD	RGD:628703
Macaca mulatta	BAALC	VGNC	VGNC:70072
Felis catus	BAALC	VGNC	VGNC:105872

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

BAALC - BAALC binder of MAP3K1 and KLF4 Gene

关于 BAALC

功能概要

BAALC 基因产物(3)

BAALC 蛋白结构

关联疾病

直系同源

热门区域

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BAALC - BAALC binder of MAP3K1 and KLF4 Gene

关于 BAALC

功能概要

BAALC 基因产物(3)

BAALC 蛋白结构

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z