2. Gene
  3. Pon1 - paraoxonase 1 Gene

Pon1 - paraoxonase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 84024 | 基因类型: protein coding

关于 Pon1

功能概要

Enables aryldialkylphosphatase activity. Involved in several processes, including response to fatty acid; response to fluoride; and response to nutrient levels. Located in extracellular space and intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); cerebrovascular disease (multiple); eye disease (multiple); glucose metabolism disease (multiple); and hematologic Cancer (multiple). Orthologous to human PON1 (paraoxonase 1). [provided by Alliance of Genome Resources, Apr 2022]

Pon1 基因产物(1)

mRNA Protein Name
NM_032077.1 NP_114466.1 serum paraoxonase/arylesterase 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables aryldialkylphosphatase activity IDA
IDA: 通过直接分析推断
11015468 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in response to fatty acid IEP
IEP: 通过表达模式推断
23383120 RGD
involved in response to fluoride IDA
IDA: 通过直接分析推断
24384758 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
29174038 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
21562236 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
23644946 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
16214326 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

serum paraoxonase/arylesterase 1

A-esterase 1

PON 1

aromatic esterase 1

serum aryldialkylphosphatase 1

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-143239 PPARα/γ agonist 1 Agonist 99.69% 否
HY-W015892 γ-Hexalactone 99.77% 否
HY-B0815S Chlorpyrifos-d10 Inhibitor 99.49% 否
HY-130220 (±)5-HETE lactone / 否
HY-146058 NF-κB/PON1-IN-1 Inhibitor / 否
HY-RS10872 PON1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17965 Pon1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24436 Pon1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-W017445 Homogentisic acid lactone Inhibitor 99.11% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pon1 NCBI NCBI:5444
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