2. Gene
  3. GCNT3 - glucosaminyl (N-acetyl) transferase 3, mucin type Gene

GCNT3 - glucosaminyl (N-acetyl) transferase 3, mucin type Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：氨基葡萄糖 (N-乙酰基) 转移酶 3，粘蛋白型

种属: Homo sapiens

同用名: GNTM; C24GNT; C2GNT2; C2GNTM; C2/4GnT

基因 ID: 9245 | 基因类型: protein coding

关于 GCNT3

Cytogenetic location: 15q22.2 Genomic coordinates (GRCh38): 15:59,549,039-59,622,723 (from NCBI)

This gene has 10 transcripts (splice variants), 274 orthologues and 8 paralogues. Biased expression in colon (RPKM 74.9), small intestine (RPKM 64.2) and 7 other tissues.

功能概要

该基因编码 N-乙酰葡糖胺基转移酶家族的成员。编码的蛋白质是一种β-6-N-乙酰葡糖胺转移酶，可催化粘蛋白型糖蛋白上核心 2 和核心 4 O-聚糖的形成。[RefSeq 提供，2009 年 4 月]

This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.[provided by RefSeq, Apr 2009]

GCNT3 基因产物(1)

mRNA Protein Name
NM_004751.3 NP_004742.1 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

GCNT3 蛋白结构

Branch

Branch: Core-2/I-Branching enzyme (133 - 401)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 438 a.a.
蛋白主名 其他名称

beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3

C2GnT-mucin type

关联疾病

疾病名称 别名
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05341 GCNT3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21579 Gcnt3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus GCNT3 RGD RGD:631333
Macaca mulatta GCNT3 VGNC VGNC:84342
Felis catus GCNT3 VGNC VGNC:104351
Mus musculus GCNT3 MGD MGI:1919327
Canis familiaris GCNT3 VGNC VGNC:59113
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