2. Gene
  3. SLC22A13 - solute carrier family 22 member 13 Gene

SLC22A13 - solute carrier family 22 member 13 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 22 成员 13

种属: Homo sapiens

同用名: OAT10; OCTL1; OCTL3; ORCTL3; ORCTL-3

基因 ID: 9390 | 基因类型: protein coding

关于 SLC22A13

Cytogenetic location: 3p22.2 Genomic coordinates (GRCh38): 3:38,265,812-38,278,757 (from NCBI)

This gene has 3 transcripts (splice variants), 325 orthologues and 22 paralogues. Restricted expression toward kidney (RPKM 6.8).

功能概要

该基因编码有机阳离子转运蛋白家族的一个成员。它与该家族的另一个成员有机阳离子转运蛋白如 4 位于一个基因簇中。编码的蛋白质是参与小分子转运的跨膜蛋白。这种蛋白质可以起到介导尿酸盐摄取的作用，并且是肾脏和肠道中的高亲和力烟酸盐交换剂。[RefSeq 提供，2008 年 9 月]

This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine. [provided by RefSeq, Sep 2008]

SLC22A13 基因产物(1)

mRNA Protein Name
NM_004256.4 NP_004247.2 solute carrier family 22 member 13
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables nicotinate transmembrane transporter activity EXP
EXP: 通过实验结果推断
18411268 GOA
enables nicotinate transmembrane transporter activity IDA
IDA: 通过直接分析推断
18411268 GOA
enables urate transmembrane transporter activity IDA
IDA: 通过直接分析推断
18411268 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of fatty acid metabolic process IDA
IDA: 通过直接分析推断
24769897 GOA
involved in nicotinate transport IDA
IDA: 通过直接分析推断
18411268 GOA
involved in positive regulation of T cell mediated cytotoxicity directed against tumor cell target IDA
IDA: 通过直接分析推断
19282870 GOA
involved in urate transport IDA
IDA: 通过直接分析推断
18411268 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in Golgi apparatus IDA
IDA: 通过直接分析推断
19282870 GOA
located in apical plasma membrane IDA
IDA: 通过直接分析推断
18411268 GOA
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
19282870 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
19282870 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC22A13 蛋白结构

Sugar_tr

Sugar_tr: Sugar (and other) transporter (140 - 508)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 551 a.a.
蛋白主名 其他名称

solute carrier family 22 member 13

organic anion transporter 10

关联疾病

疾病名称 别名
Nephrolithiasis, Uric Acid

Nephrolithiasis, Uric Acid, Susceptibility To

Uric Acid Urolithiasis

Uric Acid Nephrolithiasis

UAN

Acute Urate Nephropathy

Urolithiasis, Uric Acid

Urolithiasis, Uric Acid, Susceptibility To

Uric Acid Renal Calculus
Gout

Gouty Arthritis

Articular Gout

Gouty Arthropathy

Arthritis, Gouty

Arthritis Gouty

Idiopathic Gout

Idiopathic Gout, Unspecified Site

Gouty Bursitis

Uratic Arthritis

Gout Nos

Gouty

Gouty Diathesis
Renal Glucosuria

Renal Glycosuria

Familial Renal Glucosuria

GLYS

Glys1

Glycosuria, Renal

Glucosuria, Renal

Renal Diabetes

Familial Renal Glycosuria

Sglt2 Deficiency

Gly

Diabetes Renal
Brown-Vialetto-Van Laere Syndrome 2

BVVLS2

Rfvt3-Related Riboflavin Transporter Deficiency

Rtd3

Riboflavin Transporter Deficiency 3

Brown-Vialetto-Van Laere Syndrome, Type 2
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13066 SLC22A13 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22071 Slc22a13 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta SLC22A13 VGNC VGNC:77593
Rattus norvegicus SLC22A13 RGD RGD:1583222
Canis familiaris SLC22A13 VGNC VGNC:46274
Felis catus SLC22A13 VGNC VGNC:68653
Mus musculus SLC22A13 MGD MGI:2143107
Bos taurus SLC22A13 VGNC VGNC:34721
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