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  5. Gentisin

Gentisin 是一种天然化合物。Gentisin 可以从 Gentianae radix (Gentianaceae) 提取得到。Gentisin 具有诱变活性。Gentisin 可用于血管平滑肌研究。

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Gentisin

Gentisin Chemical Structure

CAS No. : 437-50-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gentisin is a natural compound. Gentisin can be extracted from Gentianae radix (Gentianaceae). Gentisin has mutagenic activity. Gentisin can be used in vascular smooth muscle research[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
103.76 μM
Compound: 6
Cytotoxicity against Taxol-resistant human A549 cells measured after 48 hrs by MTT assay
Cytotoxicity against Taxol-resistant human A549 cells measured after 48 hrs by MTT assay
[PMID: 28065566]
NCI/ADR-RES IC50
31.82 μM
Compound: 6
Cytotoxicity against human MCF7/ADR cells measured after 48 hrs by MTT assay
Cytotoxicity against human MCF7/ADR cells measured after 48 hrs by MTT assay
[PMID: 28065566]
SMMC-7721 IC50
87.44 μM
Compound: 6
Cytotoxicity against Taxol-resistant human SMMC7721 cells measured after 48 hrs by MTT assay
Cytotoxicity against Taxol-resistant human SMMC7721 cells measured after 48 hrs by MTT assay
[PMID: 28065566]
体外研究
(In Vitro)

Gentisin (1-30 µM; 48 h) 以浓度依赖性方式抑制 PDGF 诱导的血管平滑肌细胞增殖,IC50 为 7.84 µM[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

258.23

Formula

C14H10O5

CAS 号
性状

固体

颜色

Light yellow to yellow

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料

纯度: 98.88%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Gentisin
目录号:
HY-N4279
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