1. Immunology/Inflammation
  2. Glycoprotein VI
  3. GPVI antagonist 3

GPVI antagonist 3 (Compound 2) 是 Glycoprotein VI (GPVI) 的潜在拮抗剂。GPVI antagonist 3 的IC50值分别为:胶原蛋白为1.01 μM,CRP为1.92 μM,convulxin为7.24 μM,凝血酶为51.74 μM。糖蛋白 VI (GPVI) 是一种血小板主要胶原受体,是有效和安全的抗血栓研究的靶点。GPVI antagonist 3 是一种很有前途的抗血小板活性分子。

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GPVI antagonist 3 Chemical Structure

GPVI antagonist 3 Chemical Structure

CAS No. : 901654-94-2

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生物活性

GPVI antagonist 3 (Compound 2) is a potential antagonist of Glycoprotein VI (GPVI). IC50 values of GPVI antagonist 3 are, respectively, 1.01 μM for collagen, 1.92 μM for CRP, 7.24 μM for convulxin and 51.74 μM for thrombin. Glycoprotein VI (GPVI) is a platelet major collagen receptor and a target for potent and safe antithrombotic research. GPVI antagonist 3 is a promising antiplatelet agent[1].

分子量

393.44

Formula

C22H23N3O4

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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GPVI antagonist 3
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