2. Anti-infection
  3. Bacterial
  4. Gremubamab

Gremubamab  (Synonyms: MEDI3902)

目录号: HY-P99649 纯度: ≥95.0%
COA

摩尔计算器

Gremubamab (MEDI3902) 是一种人源化 IgG1 kappa 抗 PcrV/Psl 单克隆抗体。Gremubamab 结合 PA PcrV 蛋白和 Psl 胞外多糖 Gremubamab 具有研究铜绿假单胞菌感染的潜力。

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Gremubamab Chemical Structure

Gremubamab Chemical Structure

CAS No. : 1800381-36-5

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规格 价格 是否有货 数量
1 mg ￥4500
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Gremubamab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gremubamab (MEDI3902) is a humanized IgG1 kappa anti-PcrV/Psl monoclonal antibody. Gremubamab binds to the PA PcrV protein and Psl exopolysaccharide. Gremubamab has the potential for the research of pseudomonas aeruginosa infections[1][2].

体内研究
(In Vivo)

Gremubamab (1, 5, 15 mg/kg; i.v.; at 1 h postinfection) 改善兔急性肺炎模型的生存结果[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rabbits (acute pneumonia model)[2]
Dosage: 1, 5, 15 mg/kg
Administration: I.v.; at 1 h postinfection
Result: Improved survival outcomes in a dose-dependent manner in a rabbit acute pneumonia model.
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: ≥95.0%

COA (150 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Gremubamab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gremubamab1800381-36-5MEDI3902MEDI 3902MEDI-3902Bacterial格瑞巴单抗Inhibitorinhibitorinhibit

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