1. Metabolic Enzyme/Protease
  2. Isocitrate Dehydrogenase (IDH)
  3. IDH1 Inhibitor 3

IDH1 Inhibitor 3 

目录号: HY-107977
产品使用指南

IDH1 Inhibitor 3 (compound 6f) 是突变型的 IDH1 的抑制剂,其对IDH1R132HIC50 值为 45 nM。

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IDH1 Inhibitor 3 Chemical Structure

IDH1 Inhibitor 3 Chemical Structure

CAS No. : 2171081-24-4

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Description

IDH1 Inhibitor 3 (compound 6f) is a mutant isocitric dehydrogenase 1 (IDH1) inhibitor, with an IC50 of 45 nM for IDH1R132H[1].

IC50 & Target

IC50: 45 nM (IDH1R132H)[1].

Molecular Weight

591.56

Formula

C₃₁H₂₅F₄N₅O₃

CAS No.

2171081-24-4

SMILES

O=C([C@@H](CC1)N(C2=NC=CC(C#N)=C2)C1=O)N([C@@]3(C(NC4CC(F)(F)C4)=O)CCC5=C3C=CC=C5)C6=CC(F)=CC(F)=C6

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
IDH1 Inhibitor 3
目录号:
HY-107977
需求量:

IDH1 Inhibitor 3

Cat. No.: HY-107977