1. Epigenetics TGF-beta/Smad
  2. PKC
  3. K-252b

K-252b 是从放线菌Nocardiopsis中分离得到的一种吲哚卡唑,是 PKC 的一个抑制剂。K-252b 不能自由通过细胞膜,因此常被用作胞外激酶的抑制剂。

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K-252b Chemical Structure

K-252b Chemical Structure

CAS No. : 99570-78-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

K-252b, an indolocarbazole isolated from the actinomycete Nocardiopsis, is a PKC inhibitor. K-252b can be used to inhibit extracellular kinases of cells in culture because it can’t pass through cell membrane freely [1][2][3].

IC50 & Target

PKC[1].

分子量

453.45

Formula

C26H19N3O5

CAS 号
结构分类
初始来源

Nocardiopsis Sp.K-290

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

K-252b 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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