1. Anti-infection
  2. Antibiotic
  3. Kazusamycin B

Kazusamycin B  (Synonyms: PD 124895; CL-1957E)

目录号: HY-118331
产品使用指南

Kazusamycin B 是一种抗生素,可以从 Streptomyces sp. No. 81-484 的发酵液中分离出来。Kazusamycin B 抑制细胞生长并使细胞周期停滞在 G1 期。Kazusamycin B 可用于癌症研究。

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Kazusamycin B Chemical Structure

Kazusamycin B Chemical Structure

CAS No. : 107140-30-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kazusamycin B is an antibiotic that could be isolated from the fermentation broth of Streptomyces sp. No. 81-484. Kazusamycin B inhibits cell growth and arrests cell cycle at G1 phase. Kazusamycin B can be used in research of cancer[1][2].

体外研究
(In Vitro)

Kazusamycin B (PD 124895; 5 ng/mL; 24 h; 1210 cells) 具有时间依赖性的细胞毒性,使细胞周期停滞在 G1 期[2]
Kazusamycin B (5-50 ng/mL; 0-6 h; 1210 cells) 适度抑制 RNA 合成,但特异性抑制 2 小时[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cycle Analysis[2]

Cell Line: 1210 cells
Concentration: 5 ng/mL
Incubation Time: 24 h
Result: Arrested cell cycle at G1 phase at 4 hours.
分子量

542.70

Formula

C32H46O7

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Kazusamycin B 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
HY-118331
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