1. Anti-infection
  2. Fungal
  3. Kievitone

Kievitone 是一种异黄酮,是可以从 Rhizoctonia solani Kühn 感染 Phaseolus vulgaris L. 的下胚轴中分离出来。Kievitone 具有抗真菌活性和抗肿瘤活性。

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Kievitone Chemical Structure

Kievitone Chemical Structure

CAS No. : 40105-60-0

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kievitone, an isoflavanone, could be isolated from hypocotyls of Phaseolus vulgaris L. infected with Rhizoctonia solani Kühn. Kievitone has antifungal activity and antitumor activity[1][2].

体外研究
(In Vitro)

Kievitone (0-40 μM; 4 天) 抑制雌激素受体 (ER) 阳性乳腺癌细胞株 MCF-7 和 T47D 以及 ER 阴性乳腺癌细胞株 SKBR3 的增殖 (IC50 值 为 5-18 μM)[2]
Kievitone (0-40 μM; 48 h) 抑制由胰岛素样生长因子 1、胰岛素样生长因子 2、碱性成纤维细胞生长因子或转化生长因子 α 刺激的 MCF-7 细胞的 DNA 合成[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[2]

Cell Line: MCF-7, T47D and SKBR3 cells
Concentration: 0-40 μM
Incubation Time: 4 days
Result: Inhibited breast cancer cell proliferation in a dose-dependent manner.
分子量

356.37

Formula

C20H20O6

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Kievitone 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Kievitone
目录号:
HY-123351
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