1. Membrane Transporter/Ion Channel
  2. Potassium Channel
  3. KV1.3-IN-1

KV1.3-IN-1 (Compound trans-18) 是一种 KV1.3 通道抑制剂 (IC50:分别在 Ltk? 细胞和 PHA 激活的 T 淋巴细胞中为 230 nM 和 26.12 nM)。KV1.3-IN-1 损害细胞内 Ca2+ 信号传导。KV1.3-IN-1 抑制 T 细胞活化、增殖和集落形成。

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KV1.3-IN-1 Chemical Structure

KV1.3-IN-1 Chemical Structure

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

KV1.3-IN-1 (Compound trans-18) is a KV1.3 channel inhibitor (IC50: 230 nM and 26.12 nM in Ltk? cells and PHA-activated T-lymphocytes respectively). KV1.3-IN-1 impairs intracellular Ca2+ signaling. KV1.3-IN-1 inhibits T-cell activation, proliferation, and colony formation[1].

分子量

430.56

Formula

C23H30N2O4S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
KV1.3-IN-1
目录号:
HY-155516
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