2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Potassium Channel Calcium Channel
  4. Lidoflazine

Lidoflazine 是 HERG K+ 通道的高亲和力阻滞剂。Lidoflazine 也是一种抗心绞痛的钙通道阻滞剂，具有延长 QT 间期和发生室性心律失常的重大风险。

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Lidoflazine Chemical Structure

Lidoflazine Chemical Structure

CAS No. : 3416-26-0

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规格 价格 是否有货
1 mg ￥4124
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Lidoflazine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K+ channel. Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia[1].

体外研究
(In Vitro)

Lidoflazine inhibits potently HERG current (IHERG) recorded from HEK 293 cells stably expressing wild-type HERG (IC50 of ~16 nM).

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Lidoflazine 相关抗体:
分子量

491.62

Formula

C30H35F2N3O
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥98.0%

COA (260 KB)

产品使用指南 (1538 KB)
参考文献

Lidoflazine 相关分类

  • 摩尔计算器

  • 稀释计算器

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lidoflazine3416-26-0Potassium ChannelCalcium ChannelKcsACa2+ channelsCa channelsInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-112075
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