2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. LP 12 hydrochloride hydrate

LP 12 hydrochloride hydrate 

目录号: HY-103105A 纯度: ≥99.0%
COA 产品使用指南

摩尔计算器

LP 12 hydrochloride hydrate 是一种有效的选择性 5-HT7 受体激动剂，Ki 为 0.13 nM。LP 12 hydrochloride hydrate 对 5-HT7 的选择性优于 D2、5-HT1A 和 5-HT2A 受体 (Ki 值分别为 224 nM、60.9 nM 和 >1000 nM)。

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LP 12 hydrochloride hydrate Chemical Structure

LP 12 hydrochloride hydrate Chemical Structure

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规格 价格 是否有货 数量
1 mg ￥1500
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Customer Review

Other Forms of LP 12 hydrochloride hydrate:

LP 12 hydrochloride hydrate 相关抗体

Top Publications Citing Use of Products

查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LP 12 hydrochloride hydrate is a potent and selective 5-HT7 receptor agonist with a Ki of 0.13 nM. LP 12 hydrochloride hydrate displays selectivity for 5-HT7 over D2, 5-HT1A and 5-HT2A receptors (Ki values are 224 nM, 60.9 nM and >1000 nM, respectively)[1][2].

体外研究
(In Vitro)

LP 12 hydrochloride hydrate (0.13 nM; spermatozoa) increases the percentage of hyperactivated spermatozoa. LP 12 hydrochloride hydrate do not affect straight-line velocity (VSL), curvilinear velocity (VCL), average-path velocity (VAP), linearity (LIN), straightness (STR), wobbler coefficient (WOB), amplitude of lateral head displacement (ALH), and beat-cross frequency (BCF)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

LP 12 hydrochloride hydrate 相关抗体:
Formula

C32H39N3O.HCl.xH2O
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

COA (263 KB)

产品使用指南 (1538 KB)
参考文献

LP 12 hydrochloride hydrate 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LP 12 hydrochloride5-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptorpronociceptive effectshyperactivated spermatozoastraight-line velocitycurvilinear velocityInhibitorinhibitorinhibit

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目录号：
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