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  2. Reference Standards Interleukin Related NO Synthase NF-κB TNF Receptor
  3. Malvidin-3-glucoside chloride (Standard)

Malvidin-3-glucoside chloride (Standard)  (Synonyms: Malvidin-3-O-glucoside chloride (Standard); Oenin chloride (Standard))

目录号: HY-125740R 纯度: ≥98%
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Malvidin-3-glucoside (Malvidin-3-O-glucoside; Oenin) chloride (Standard) 是 Malvidin-3-glucoside chloride (HY-125740) 的分析标准品。本产品用于研究及分析应用。Malvidin-3-glucoside chloride 是口服有效的 NF-κB 通路抑制剂,可阻断 TNF-α 诱导的炎症反应,减少 IκB-α 降解及 p65 核转位,并上调内皮型一氧化氮合酶 eNOS 以增加 NO 生成。Malvidin-3-glucoside chloride 通过抑制 MCP-1ICAM-1IL-6 等促炎分子及调节肠道微生物和代谢物,发挥抗炎和抗氧化作用,同时保护内皮细胞并改善炎症状态下的肠道微生态失调。Malvidin-3-glucoside chloride 可用于研究动脉粥样硬化、炎症性肠病等慢性炎症相关疾病,具有预防血管炎症和改善肠道健康方面的潜力。

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Malvidin-3-glucoside chloride (Standard) Chemical Structure

Malvidin-3-glucoside chloride (Standard) Chemical Structure

CAS No. : 7228-78-6

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生物活性

Malvidin-3-glucoside (Malvidin-3-O-glucoside; Oenin) chloride (Standard) is the analytical standard of Malvidin-3-glucoside chloride (HY-125740). This product is intended for research and analytical applications. Malvidin-3-glucoside chloride is an orally active inhibitor of the NF-κB pathway, which blocks inflammatory responses induced by TNF-α, reduces IκB-α degradation and p65 nuclear translocation, and upregulates endothelial nitric oxide synthase eNOS to increase NO production. Malvidin-3-glucoside chloride exerts anti-inflammatory and antioxidant effects by inhibiting pro-inflammatory molecules such as MCP-1, ICAM-1, and IL-6, and regulating intestinal microorganisms and metabolites, while protecting endothelial cells and improving intestinal microecological dysbiosis under inflammatory conditions. Malvidin-3-glucoside chloride can be used to study chronic inflammatory-related diseases such as atherosclerosis and inflammatory bowel disease, and has the potential to prevent vascular inflammation and improve intestinal health.

分子量

528.89

同用名

Malvidin-3-O-glucoside chloride (Standard); Oenin chloride (Standard)

Formula

C23H25ClO12

CAS 号
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储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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