1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. Mc-Val-Cit-PAB-Cl

Mc-Val-Cit-PAB-Cl 

目录号: HY-112099
产品使用指南

Mc-Val-Cit-PAB-Cl 是一种 ADC linker,可用于连接 MMAE 和抗体,从而形成抗体-MC-vc-MMAE (如 anti-CD22-MC-VC-PABC-MMAE,对 BJAB 和 WSU 具有细胞毒性,IC50 分别为 3.3 nM 和 0.95 nM)。

MCE 的所有产品仅用作科学研究,我们不为任何个人用途提供产品和服务

Mc-Val-Cit-PAB-Cl Chemical Structure

Mc-Val-Cit-PAB-Cl Chemical Structure

CAS No. : 1639351-92-0

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

Size Stock
100 mg Get quote
250 mg Get quote
300 mg Get quote

* Please select Quantity before adding items.

Customer Review

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

Description

Mc-Val-Cit-PAB-Cl is an ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay).

IC50 & Target

Alkyl/ether

 

Molecular Weight

591.10

Formula

C₂₈H₃₉ClN₆O₆

CAS No.

1639351-92-0

SMILES

O=C(N1CCCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC2=CC=C(CCl)C=C2)=O)=O)=O)C=CC1=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Mc-Val-Cit-PAB-Cl
目录号:
HY-112099
需求量:

Mc-Val-Cit-PAB-Cl

Cat. No.: HY-112099