1. Antibody-drug Conjugate/ADC Related
  2. ADC Linker
  3. MDTF free acid

MDTF free acid 是不可降解 (non-cleavable) 的 ADC linker,用于合成抗体偶联活性分子 (ADCs)。

在相同的摩尔浓度下,化合物盐形式与游离形式有相同的生物活性,但盐形式 MDTF 通常具有更好的水溶性和稳定性。

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MDTF free acid Chemical Structure

MDTF free acid Chemical Structure

CAS No. : 2102021-49-6

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MDTF free acid 的其他形式现货产品:

Customer Review

Other Forms of MDTF free acid:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MDTF free acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

体外研究
(In Vitro)

MDTF free acid (50?μM) increases hydrophilic character by substitution of a cyclohexyl ring and a MD-based FRET probe incubates in human plasma has a considerably higher self-stabilization rate compared to the MCC-based probe[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

469.32

Formula

C16H11F4NO9S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MDTF free acid
目录号:
HY-150043
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