1. Immunology/Inflammation
  2. Transmembrane Glycoprotein
  3. MEN1112

MEN1112  (Synonyms: OBT357NF; OBT357)

目录号: HY-P991665
技术支持

MEN1112 (OBT357NF) 是一种选择性靶向 Bst1/CD157 的人源化单克隆抗体 (EC50=1 nM)。MEN1112 对急性髓系白血病 (AML) 细胞具有强大的抗肿瘤活性。MEN1112 有望用于血液系统恶性肿瘤的研究,如 AML 。

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MEN1112

MEN1112 Chemical Structure

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MEN1112 (OBT357NF) is a selective humanized monoclonal antibody targeting the Bst1/CD157 antigen (EC50=1 nM). MEN1112 exerts potent antitumor activity against acute myeloid leukemia (AML) cells. MEN1112 is promising for research of hematological malignancies such as AML[1].

同型

Human IgG1 kappa

推荐同型对照抗体
反应种属

Human

IC50 & Target

BST1/CD157

基因 ID

683  [NCBI]

Accession

Q10588

靶点

BST1/CD157

应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
MEN1112
目录号:
HY-P991665
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