1. Membrane Transporter/Ion Channel Neuronal Signaling
  2. GABA Receptor
  3. (-)-Bicuculline methochloride

(-)-Bicuculline methochloride  (Synonyms: (-)-荷包牡丹碱甲氯化物; l-Bicuculline methochloride)

目录号: HY-100783A
产品使用指南

(-)-Bicuculline methochloride (l-Bicuculline methochloride) 是一种有效的 GABAA 受体拮抗剂。(-)-Bicuculline methochloride 在神经元中阻断 Ca2+ 激活的 K+ 通道介导的后超极化 (AHPs)。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

(-)-Bicuculline methochloride Chemical Structure

(-)-Bicuculline methochloride Chemical Structure

CAS No. : 53552-05-9

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

(-)-Bicuculline methochloride 的其他形式现货产品:

Customer Review

Other Forms of (-)-Bicuculline methochloride:

注册 MCE会员完成审核
即刻享有 积分商城 300 专属积分

Top Publications Citing Use of Products
  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(-)-Bicuculline methochloride (l-Bicuculline methochloride) is a potent GABAA receptor antagonist. (-)-Bicuculline methochloride blocks afterhyperpolarizations (AHPs) mediated by Ca2+-activated K+ channels in various types of neurons[1].

IC50 & Target

GABAA[1]

体内研究
(In Vivo)

(-)-Bicuculline methochloride (0.6 nmol/rat) attenuates the antiallodynic effect of Neurotropin[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Rat L5-SNL model[2]
Dosage: 0.6 nmol/rat
Administration: Intrathecal injection, 5 minutes before administration of Neurotropin (100 NU/kg, i.v.)
Result: Attenuated the antiallodynic effect of Neurotropin.
分子量

417.84

Formula

C21H20ClNO6

CAS 号
中文名称

(-)-荷包牡丹碱甲氯化物; (-)-比枯枯灵甲氯化物

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

(-)-Bicuculline methochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
(-)-Bicuculline methochloride
目录号:
HY-100783A
需求量: